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- Transition from the Middle Ages to the modern era
* Renaissance spreads to the rest of Europe
* Development of capitalism, banking, merchantilism and accounting: beginning of the European Great Divergence
* Explorers from the Italian maritime republics serve under the auspices of European monarchs, ushering in the Age of Discovery
* Rediscovery and restoration of humanism and of Greco-Roman culture
* Renaissance literature, painting, sculpture, architecture and music have a profound impact on the evolution of the arts
* Renaissance wars lead to significant changes in the history of diplomacy and warfare
* Italian universities play a significant role in the beginning of the Scientific Revolution
* Increase of papal temporal power leads to the Reformation, the Counter-Reformation and the European wars of religion (en)
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