National responses to the COVID-19 pandemic have been varied, and have included containment measures such as lockdowns, quarantines, and curfews. As of 8 December 2022, 646,912,296 cases of COVID-19 have been reported, resulting in 6,646,070 reported deaths. The most affected countries in terms of confirmed cases are the United States, Brazil, India, Russia, South Africa, Peru, Mexico, Chile, the United Kingdom, and Iran.