| dbo:description
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- 脳の様々な領域で覚醒や刺激を減少させるか抑制し、神経伝達の水準を低下させる薬物や内因性の化合物 (ja)
- medicamentos que reducen los niveles de neurotransmisión, reduciendo la actividad cerebral (es)
- Drogen mit beruhigender Wirkung (de)
- дрога или ендогено једињење које снижава нивое неуротрансмисија (sr)
- aineryhmä (fi)
- farmaco psicotropo che esercita azione deprimente sull'attività mentale (it)
- substance qui ralentit l'activité du système nerveux central (fr)
- компонент или лекарство, которое снижает уровень нейротрансмиссии (ru)
- zdravilo ali endogena spojina, ki znižuje raven živčnega prenosa (sl)
- drug or endogenous compound that lowers neurotransmission levels (en)
- תרופה או תרכובת אנדוגנית המורידה את רמות ההולכה העצבית (iw)
- nörotransmisyon seviyelerini düşüren ilaç veya endojen bileşik (tr)
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| dbp:align
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| dbp:alt
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- 5 (xsd:integer)
- dbr:Papaver_somniferum
- dbr:Zaleplon
- dbr:Zolpidem
- GABA analogues (en)
- Binding sites of pregabalin and the non-gabapentenoid ziconotide to the voltage-gated calcium channel complex. (en)
- The rostromedial tegmental nucleus is located in the midbrain of the brainstem. The release of dopamine in the RMTg characterizes the euphoria and reinforcement of opioids. (en)
- Severity of GHB withdrawal syndrome (en)
- GHB that is used to treat alcohol addiction in Italy. (en)
- When the μ-opioid receptor is activated on a neuron, the voltage-gated calcium channel closes and the voltage-gated potassium channel opens. Both of these individual actions make the presynaptic neuron less likely to release glutamate , leaving the neuron at rest longer. This slowing down of neurons via interactions with ion channels and receptors is a hallmark of a depressant. Without glutamate the pain signal gets "cut short" and cannot ascend a pathway and reach pain processing centers in the midbrain of the brainstem. (en)
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| dbp:biologicalTarget
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| dbp:caption
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- dbr:Papaver_somniferum
- dbr:Zaleplon
- dbr:Zolpidem
- dbr:Voltage-gated_calcium_channel
- GABA analogues (en)
- The rostromedial tegmental nucleus is located in the midbrain of the brainstem. The release of dopamine in the RMTg characterizes the euphoria and reinforcement of opioids. (en)
- Baclofen tablets (en)
- Methaqualone tablets (en)
- Nitromethaqualone structure (en)
- Oxycodone is a semi-synthetic prescription opioid. (en)
- Severity of GHB withdrawal syndrome (en)
- Chemical structure of alcohol , among the most well-known and widely used central depressants. (en)
- GHB that is used to treat alcohol addiction in Italy. (en)
- When the μ-opioid receptor is activated on a neuron, the voltage-gated calcium channel closes and the voltage-gated potassium channel opens. Both of these individual actions make the presynaptic neuron less likely to release glutamate , leaving the neuron at rest longer. This slowing down of neurons via interactions with ion channels and receptors is a hallmark of a depressant. Without glutamate the pain signal gets "cut short" and cannot ascend a pathway and reach pain processing centers in the midbrain of the brainstem. (en)
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| dbp:chemicalClass
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| dbp:direction
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- vertical (en)
- horizontal (en)
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| dbp:image
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- Phenibut and analogues.png (en)
- Voltage gated calcium channel.jpg (en)
- Oriental poppies gone wild - geograph.org.uk - 1397319.jpg (en)
- Alcover 17,5 - Gamma-Hydroxybutyric acid.JPG (en)
- Baclosan.JPG (en)
- GHB withdrawal symptoms.png (en)
- Midbrain small.gif (en)
- Mu opioid receptor.svg (en)
- Nitromethaqualone.svg (en)
- OnyNorm förpackning.jpg (en)
- Sonata10mg.JPG (en)
- Zolpidem.svg (en)
- Метаквалон.jpg (en)
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| dbp:legalStatus
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| dbp:mechanismOfAction
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| dbp:synonyms
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- Central depressant; Central nervous system depressant; CNS depressant; Downer; Sedative; Tranquilizer (en)
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| dbp:totalWidth
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- 180 (xsd:integer)
- 280 (xsd:integer)
- 300 (xsd:integer)
- 500 (xsd:integer)
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| dbp:width
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| dbp:wikiPageUsesTemplate
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| dct:subject
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| gold:hypernym
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| rdf:type
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| rdfs:label
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- Depressant (en)
- Depressor (ca)
- عقاقير مسببة للاكتئاب (ar)
- Downer (Drogen) (de)
- Depresor (es)
- Dépresseur (fr)
- 抑制剤 (ja)
- Depressor (pt)
- Depresanty (pl)
- Депресанти (uk)
- Депрессанты (ru)
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