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- A GABA receptor agonist is a drug that is an agonist for one or more of the GABA receptors, producing typically sedative effects, and may also cause other effects such as anxiolytic, anticonvulsant, and muscle relaxant effects. There are three receptors of the gamma-aminobutyric acid. The two receptors GABA-α and GABA-ρ are ion channels that are permeable to chloride ions which reduces neuronal excitability. The GABA-β receptor belongs to the class of G-Protein coupled receptors that inhibit adenylyl cyclase, therefore leading to decreased cyclic adenosine monophosphate (cAMP). GABA-α and GABA-ρ receptors produce sedative and hypnotic effects and have anti-convulsion properties. GABA-β receptors also produce sedative effects. Furthermore, they lead to changes in gene transcription. (en)
- GABA受容体作動薬（GABA receptor agonist）またはGABAアゴニスト (GABA agonist) は、GABA受容体の作用を刺激または増加させる薬物で、通常は鎮静作用を持つほか、抗不安作用、抗痙攣作用、筋弛緩作用などを持つこともある薬物である。γ-アミノ酪酸の受容体は3種類ある。GABAA受容体およびGABAA-ρ受容体の2種類は、神経細胞の興奮性を低下させる塩化物イオンが透過するイオンチャネルである。GABAB受容体は、アデニル酸シクラーゼを阻害し、環状アデノシン一リン酸（cAMP）を減少させるGタンパク質共役受容体に属する。GABAAおよびGABAA-ρ受容体は、鎮静作用、催眠作用、抗痙攣作用を示し、GABAB受容体は鎮静作用をもたらす。さらに、遺伝子の転写を変化させる。 (ja)
- Um agonista do receptor GABA é uma classe farmacológica de drogas que agonizam um ou mais dos receptores GABA, produzindo efeitos sedativos e, em alguns fármacos, podem exercer propriedades ansiolíticas, anticonvulsivantes e/ou relaxante muscular. (pt)
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- A GABA receptor agonist is a drug that is an agonist for one or more of the GABA receptors, producing typically sedative effects, and may also cause other effects such as anxiolytic, anticonvulsant, and muscle relaxant effects. There are three receptors of the gamma-aminobutyric acid. The two receptors GABA-α and GABA-ρ are ion channels that are permeable to chloride ions which reduces neuronal excitability. The GABA-β receptor belongs to the class of G-Protein coupled receptors that inhibit adenylyl cyclase, therefore leading to decreased cyclic adenosine monophosphate (cAMP). GABA-α and GABA-ρ receptors produce sedative and hypnotic effects and have anti-convulsion properties. GABA-β receptors also produce sedative effects. Furthermore, they lead to changes in gene transcription. (en)
- GABA受容体作動薬（GABA receptor agonist）またはGABAアゴニスト (GABA agonist) は、GABA受容体の作用を刺激または増加させる薬物で、通常は鎮静作用を持つほか、抗不安作用、抗痙攣作用、筋弛緩作用などを持つこともある薬物である。γ-アミノ酪酸の受容体は3種類ある。GABAA受容体およびGABAA-ρ受容体の2種類は、神経細胞の興奮性を低下させる塩化物イオンが透過するイオンチャネルである。GABAB受容体は、アデニル酸シクラーゼを阻害し、環状アデノシン一リン酸（cAMP）を減少させるGタンパク質共役受容体に属する。GABAAおよびGABAA-ρ受容体は、鎮静作用、催眠作用、抗痙攣作用を示し、GABAB受容体は鎮静作用をもたらす。さらに、遺伝子の転写を変化させる。 (ja)
- Um agonista do receptor GABA é uma classe farmacológica de drogas que agonizam um ou mais dos receptores GABA, produzindo efeitos sedativos e, em alguns fármacos, podem exercer propriedades ansiolíticas, anticonvulsivantes e/ou relaxante muscular. (pt)
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- GABA receptor agonist (en)
- GABA受容体作動薬 (ja)
- Agonista do receptor GABA (pt)
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