About: Bupropion

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Substituted cathinone medication mainly for depression and smoking cessation

Property Value
dbo:alternativeName
  • Wellbutrin, Zyban, others (en)
dbo:casNumber
  • 31677-93-7 (HCl)
  • 34911-55-2
  • 905818-69-1HBr)
dbo:chEBI
  • 3219
dbo:chEMBL
  • 894
dbo:class
dbo:description
  • cheemesch Verbindung (lb)
  • chemická sloučenina (cs)
  • chemická zlúčenina (sk)
  • chemiese verbinding (af)
  • chemische Verbindung (de)
  • chemische verbinding (nl)
  • component quimic (oc)
  • compositum chemicum (la)
  • compost químic (ca)
  • composto químico (gl)
  • composto químico (pt)
  • composé chimique (fr)
  • compuesto quimico (an)
  • compuestu químicu (ast)
  • compus chimic (ro)
  • kemia kombinaĵo (eo)
  • kemiallinen yhdiste (fi)
  • kemisk forbindelse (da)
  • kjemisk sambinding (nn)
  • komponim kimik (sq)
  • konposatu kimiko (eu)
  • senyawa kimia (in)
  • związek chemiczny (pl)
  • ķīmisks savienojums (lv)
  • хемиско соединение (mk)
  • хімічна сполука (uk)
  • քիմիական միացություն (hy)
  • کیٖمیٲیی مُرَکَب (ks)
  • রাসায়নিক যৌগ (bn)
  • രാസസം‌യുക്തം (ml)
  • compuesto químico (es)
  • תרכובת (iw)
  • farmaco (it)
  • ఔషధం (te)
  • ଯୌଗିକ ରାସାୟନିକ ପଦାର୍ଥ (or)
  • substituted cathinone medication mainly for depression and smoking cessation (en)
  • atípusos antidepresszáns gyógyszer (hu)
  • 主要用於憂鬱症與戒菸的卡西酮替代藥物 (zh)
  • läkemedel som används som antidepressivum (sv)
  • химическое соединение, использующееся как лекарственное средство (атипичный антидепрессант) (ru)
  • داروی برای درمان اختلال افسردگی عمده یا ترک سیگار (fa)
  • depresyon ve sigarayı bırakma için ikame edilmiş katinon ilacı (tr)
  • atipični noradrenalin-dopaminergički antidepresiv (hr)
  • دواء يستخدم في المقام الأول مضاداً للاكتئاب وللإقلاع عن التدخين (ar)
dbo:drugbank
  • DB01156
dbo:fdaUniiCode
  • 01ZG3TPX31
dbo:kegg
  • D00817
  • D07591
dbo:medlinePlus
  • a695033
dbo:pubchem
  • 444
dbo:thumbnail
dbo:wikiPageExternalLink
dbo:wikiPageWikiLink
dbp:align
  • center (en)
dbp:alt
  • Ball-and-stick model of the isomer of the bupropion molecule (en)
  • Bupropion synthesis diagram (en)
  • Skeletal formula of bupropion (en)
dbp:annotColor
  • var (en)
dbp:annotFontSize
  • 14 (xsd:integer)
dbp:annotTextAlign
  • center (en)
dbp:atcPrefix
  • N06 (en)
dbp:atcSuffix
  • AX12 (en)
dbp:bioavailability
  • Unknown (en)
dbp:c
  • 13 (xsd:integer)
dbp:caption
  • 1 (xsd:integer)
  • Diagram showing the synthesis of bupropion from 3'-chloro-propiophenone. The α-carbon atom is an asymmetric one, tetraedrical HC*MeNH. So, bupropion is a chiral compound. (en)
dbp:casNumber
  • 34911 (xsd:integer)
dbp:casSupplemental
  • 31677 (xsd:integer)
  • 905818 (xsd:integer)
dbp:chebi
  • 3219 (xsd:integer)
dbp:chembl
  • 894 (xsd:integer)
dbp:chemspiderid
  • 431 (xsd:integer)
dbp:cl
  • 1 (xsd:integer)
dbp:class
  • skin-invert-image (en)
  • Norepinephrine–dopamine reuptake inhibitor antidepressants (en)
dbp:dailymedid
  • Bupropion (en)
dbp:date
  • May 2023 (en)
dbp:displayAuthors
  • 6 (xsd:integer)
dbp:drugbank
  • DB01156 (en)
dbp:eliminationHalfLife
  • 39600.0 (dbd:second)
  • Bupropion: (en)
  • Erythrohydrobupropion:33h (en)
  • Hydroxybupropion:20h (en)
  • Threohydrobupropion:37h (en)
  • alpha: 0.5–1.04 (en)
dbp:excretion
  • 87.0 (dbd:second)
  • Feces: 10% (en)
dbp:h
  • 18 (xsd:integer)
dbp:height
  • 120 (xsd:integer)
dbp:icon
  • none (en)
dbp:image
  • Bupropion stereoisomers ball-and-stick models from xtal 2011.png (en)
dbp:imageBgColor
  • light-dark (en)
dbp:imageClass
  • skin-invert-image (en)
dbp:imageLeft
  • 30 (xsd:integer)
dbp:imageTop
  • 0 (xsd:integer)
dbp:imageWidth
  • 600 (xsd:integer)
dbp:index2Label
  • as HCl (en)
dbp:iupacName
  • -2 (xsd:integer)
dbp:iupharLigand
  • 7135 (xsd:integer)
dbp:kegg
  • D00817 (en)
  • D07591 (en)
dbp:legalAu
  • S4 (en)
dbp:legalBr
  • 1.0 (dbd:nicaraguanCórdoba)
dbp:legalCa
  • Rx-only (en)
dbp:legalEu
  • Rx-only (en)
dbp:legalStatus
  • Rx-only (en)
dbp:legalUk
  • POM (en)
dbp:legalUs
  • Rx-only (en)
dbp:medlineplus
  • a695033 (en)
dbp:metabolism
  • Liver, intestines (en)
dbp:metabolites
  • •Erythrohydrobupropion (en)
  • •Hydroxybupropion (en)
  • •Others (en)
  • •Threohydrobupropion (en)
dbp:n
  • 1 (xsd:integer)
dbp:nameListStyle
  • vanc (en)
dbp:o
  • 1 (xsd:integer)
dbp:pregnancyAu
  • B2 (en)
dbp:pronounce
  • Amfebutamone: (en)
  • Bupropion: (en)
dbp:proteinBound
  • Bupropion: 84% (en)
  • Hydroxybupropion: 77% (en)
  • Threohydrobupropion: 42% (en)
dbp:pubchem
  • 444 (xsd:integer)
dbp:reason
  • Per the cited source, while the statistically significant differences in response rate did indeed demonstrate that aripiprazole augmentation produced a somewhat higher response rate , there was no statistically significant difference between them in the remission rate . Simplifying this result to "bupropion augmentation is inferior to aripiprazole augmentation" as was done here is an incredibly misleading oversimplification of the actual results of the scientific research being cited to support this assertion. (en)
dbp:routesOfAdministration
dbp:smiles
  • O=CC1=CC=CC=C1 (en)
dbp:stdinchi
  • 1 (xsd:integer)
dbp:stdinchikey
  • SNPPWIUOZRMYNY-UHFFFAOYSA-N (en)
dbp:synonyms
  • 3 (xsd:integer)
  • Amfebutamone; 3-Chloro-N-tert-butyl-β-keto-α-methylphenethylamine; (en)
dbp:tradename
  • Wellbutrin, Zyban, others (en)
dbp:unii
  • 1 (xsd:integer)
dbp:verifiedfields
  • correct (en)
dbp:verifiedrevid
  • 852547309 (xsd:integer)
dbp:watchedfields
  • correct (en)
dbp:width
  • 300 (xsd:integer)
  • 680 (xsd:integer)
dbp:wikiPageUsesTemplate
dct:subject
gold:hypernym
rdf:type
rdfs:label
  • Bupropion (en)
  • Bupropió (ca)
  • Βουπροπιόνη (el)
  • بوبروبيون (ar)
  • Bupropión (es)
  • Bupropion (de)
  • Bupropion (in)
  • ブプロピオン (ja)
  • Bupropion (fr)
  • Bupropione (it)
  • 부프로피온 (ko)
  • Bupropion (pl)
  • Bupropion (nl)
  • Bupropiona (pt)
  • Бупропіон (uk)
  • Бупропион (ru)
  • Bupropion (sv)
  • 安非他酮 (zh)
rdfs:seeAlso
owl:differentFrom
owl:sameAs
prov:wasDerivedFrom
foaf:depiction
foaf:isPrimaryTopicOf
is dbo:knownFor of
is dbo:license of
is dbo:medication of
is dbo:wikiPageRedirects of
is dbo:wikiPageWikiLink of
is dbp:agonists of
is dbp:medication of
is rdfs:seeAlso of
is owl:differentFrom of
is foaf:primaryTopic of
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