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The accessible surface area (ASA) or solvent-accessible surface area (SASA) is the surface area of a biomolecule that is accessible to a solvent. Measurement of ASA is usually described in units of square angstroms (a standard unit of measurement in molecular biology). ASA was first described by Lee & Richards in 1971 and is sometimes called the Lee-Richards molecular surface. ASA is typically calculated using the 'rolling ball' algorithm developed by Shrake & Rupley in 1973. This algorithm uses a sphere (of solvent) of a particular radius to 'probe' the surface of the molecule.

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  • The accessible surface area (ASA) or solvent-accessible surface area (SASA) is the surface area of a biomolecule that is accessible to a solvent. Measurement of ASA is usually described in units of square angstroms (a standard unit of measurement in molecular biology). ASA was first described by Lee & Richards in 1971 and is sometimes called the Lee-Richards molecular surface. ASA is typically calculated using the 'rolling ball' algorithm developed by Shrake & Rupley in 1973. This algorithm uses a sphere (of solvent) of a particular radius to 'probe' the surface of the molecule. (en)
  • L'area superficiale accessibile (ASA, dall'inglese accessible surface area) è l'area superficiale di una molecola che è accessibile a un solvente. L'ASA viene solitamente riportata in Å2 ed è stata descritta originariamente da Lee e Richards nel 1971, motivo per cui viene talvolta chiamata superficie molecolare di Lee-Richards. L'ASA viene tipicamente calcolata utilizzando l'algoritmo della "palla rotolante" (rolling ball) sviluppato da Shrake e Rupley nel 1973. Questo algoritmo utilizza una sfera di un dato raggio per rappresentare il solvente, "sondando" in questo modo la superficie della molecola. (it)
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  • The accessible surface area (ASA) or solvent-accessible surface area (SASA) is the surface area of a biomolecule that is accessible to a solvent. Measurement of ASA is usually described in units of square angstroms (a standard unit of measurement in molecular biology). ASA was first described by Lee & Richards in 1971 and is sometimes called the Lee-Richards molecular surface. ASA is typically calculated using the 'rolling ball' algorithm developed by Shrake & Rupley in 1973. This algorithm uses a sphere (of solvent) of a particular radius to 'probe' the surface of the molecule. (en)
  • L'area superficiale accessibile (ASA, dall'inglese accessible surface area) è l'area superficiale di una molecola che è accessibile a un solvente. L'ASA viene solitamente riportata in Å2 ed è stata descritta originariamente da Lee e Richards nel 1971, motivo per cui viene talvolta chiamata superficie molecolare di Lee-Richards. L'ASA viene tipicamente calcolata utilizzando l'algoritmo della "palla rotolante" (rolling ball) sviluppato da Shrake e Rupley nel 1973. Questo algoritmo utilizza una sfera di un dato raggio per rappresentare il solvente, "sondando" in questo modo la superficie della molecola. (it)
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  • Accessible surface area (en)
  • Area superficiale accessibile (it)
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