About: Dutasteride

Property	Value
dbo:alternativeName	Avodart, others (en)
dbo:bioavailability	60.000000 (xsd:float)
dbo:casNumber	164656-23-9
dbo:chEBI	521033
dbo:chEMBL	1200969
dbo:class	dbr:5α-Reductase_inhibitor
dbo:description	cheemesch Verbindung (lb) chemická sloučenina (cs) chemická zlúčenina (sk) chemiese verbinding (af) chemische verbinding (nl) component quimic (oc) compositum chemicum (la) compost químic (ca) composto químico (gl) composto químico (pt) compuesto quimico (an) compuestu químicu (ast) compus chimic (ro) kemia kombinaĵo (eo) kemiallinen yhdiste (fi) kemisk forbindelse (da) kjemisk sambinding (nn) komponim kimik (sq) konposatu kimiko (eu) senyawa kimia (in) związek chemiczny (pl) ķīmisks savienojums (lv) хемиско соединение (mk) хімічна сполука (uk) քիմիական միացություն (hy) مركب كيميائي (ar) کیٖمیٲیی مُرَکَب (ks) রাসায়নিক যৌগ (bn) രാസസം‌യുക്തം (ml) תרכובת (iw) farmaco (it) Arzneistoff (de) médicament (fr) ଯୌଗିକ ରାସାୟନିକ ପଦାର୍ଥ (or) hormone replacement medication (en) medicamento (es)
dbo:drugbank	DB01126
dbo:fdaUniiCode	O0J6XJN02I
dbo:kegg	D03820
dbo:medlinePlus	a603001
dbo:pubchem	6918296
dbo:thumbnail	wiki-commons:Special:FilePath/Dutasteride.svg?width=300
dbo:wikiPageExternalLink	https://druginfo.nlm.nih.gov/drugportal/name/dutasteride
dbo:wikiPageWikiLink	dbr:Acne dbr:Antidote dbr:Isozyme dbr:Prostate-specific_antigen dbr:Tamsulosin dbr:Australia dbr:Feces dbr:Headache dbr:Japan dbr:Metabolism dbr:South_Africa dbr:South_Korea dbr:United_Kingdom dbr:Suicide_inhibition dbr:American_Urological_Association dbr:Canada dbr:Ireland dbr:Liver dbr:Semen dbr:Capsule_(pharmacy) dbr:Erectile_dysfunction dbr:Androstane dbc:Carboxamides dbc:Trifluoromethyl_compounds dbr:Antidepressant dbr:Anxiolytic dbr:Depression_(mood) dbr:Dizziness dbr:Latin_America dbr:Menstruation dbr:Pregnancy dbr:Fetus dbr:Oil dbr:Progesterone dbr:Blood_donation dbr:Mortality_rate dbr:Functional_group dbr:Boxed_warning dbr:Structural_analog dbr:Benign_prostatic_hyperplasia dbr:Gelatin dbr:Generic_drug dbr:Placebo dbr:Scientific_literature dbr:Meta-analysis dbr:Competitive_inhibition dbr:Estrogen_(medication) dbr:Allopregnanolone dbr:Neurosteroid dbr:Dutasteride/tamsulosin dbr:Neurosteroidogenesis_inhibitor dbr:Birth_defect dbr:Urine dbr:Antiandrogen dbr:Breast_cancer dbr:Prostate_cancer dbr:Libido dbr:Steroid dbr:Bioavailability dbr:Pattern_hair_loss dbr:Bicalutamide dbr:Patent dbr:Gynecomastia dbr:Sexual_dysfunction dbr:Off-label_use dbr:5α-Reductase_inhibitor dbr:CYP3A4 dbr:Enzyme_inhibitor dbr:Finasteride dbr:Potency_(pharmacology) dbr:Elimination_(pharmacology) dbr:Symptom dbr:Alfuzosin dbr:Premenstrual_dysphoric_disorder dbr:GABAA_receptor dbr:Spironolactone dbr:Chemoprophylaxis dbr:Moiety_(chemistry) dbc:5α-Reductase_inhibitors dbr:Angioedema dbr:Oral_administration dbr:Side_effect dbr:Hypersensitivity dbr:Metabolite dbr:SRD5A1 dbr:Nocebo dbr:Grading_(tumors) dbr:Hirsutism dbr:Cmax_(pharmacology) dbc:Diketones dbc:Hair_removal dbc:Wikipedia_medicine_articles_ready_to_translate dbc:Lactams dbr:Deoxycorticosterone dbc:Hormonal_antineoplastic_drugs dbc:Teratogens dbr:Tolerability dbr:Ambiguous_genitalia dbc:Hair_loss_medications dbr:Human_sexual_behavior dbr:Isoform dbc:Prostate_cancer dbc:Androstanes dbr:SRD5A3 dbr:Food_and_Drug_Administration_(United_States) dbr:SRD5A2 dbr:Transgender_women dbr:Generic_term dbr:Positive_allosteric_modulator dbr:Hypospermia dbr:GlaxoSmithKline dbr:Animal_research dbr:Overdose dbr:Prostate_gland dbr:Drug_safety dbr:Absorption_(pharmacokinetics) dbr:Gastrointestinal_discomfort dbr:Isoenzyme dbr:Elimination_half-life dbr:3α-androstanediol dbr:4-azasteroid dbr:5α-reductase_deficiency dbr:Cochrane_review dbr:Loss_of_libido dbr:Generic_medication dbr:Irreversible_inhibition dbr:Patent_protection dbr:Renal_impairment dbr:Synthetic_compound dbr:Off-label dbr:Steady_state_(pharmacokinetics) dbr:Terminal_half-life dbr:Skin_reaction dbr:Transgender_hormone_therapy_(male-to-female) dbr:File:Avodart.jpg
dbp:atcPrefix	G04 (en)
dbp:atcSuffix	CB02 (en)
dbp:bioavailability	60.0 (dbd:perCent)
dbp:c	27 (xsd:integer)
dbp:casNumber	164656 (xsd:integer)
dbp:chebi	521033 (xsd:integer)
dbp:chembl	1200969 (xsd:integer)
dbp:chemspiderid	5293502 (xsd:integer)
dbp:class	5 (xsd:integer)
dbp:dailymedid	Dutasteride (en)
dbp:density	1.346000 (xsd:double)
dbp:densityNotes	at 294 K (en)
dbp:displayAuthors	6 (xsd:integer)
dbp:drugbank	DB01126 (en)
dbp:eliminationHalfLife	4 (xsd:integer)
dbp:excretion	Feces: 40% (en) Urine: 5% (en)
dbp:f	6 (xsd:integer)
dbp:h	30 (xsd:integer)
dbp:imageClass	skin-invert-image (en)
dbp:iupacName	-N-[2,5-bisphenyl]-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide (en)
dbp:iupharLigand	7457 (xsd:integer)
dbp:kegg	D03820 (en)
dbp:legalUk	POM (en)
dbp:legalUs	Rx-only (en)
dbp:medlineplus	a603001 (en)
dbp:metabolism	Liver (en)
dbp:metabolites	(en) • 1,2-Dihydrodutasteride (en) • 4'-Hydroxydutasteride (en) • 6'-Hydroxydutasteride (en)
dbp:n	2 (xsd:integer)
dbp:nameListStyle	vanc (en)
dbp:o	2 (xsd:integer)
dbp:pregnancyCategory	Not to be used during pregnancy (en)
dbp:proteinBound	99.0 (dbd:perCent)
dbp:pubchem	6918296 (xsd:integer)
dbp:routesOfAdministration	dbr:Oral_administration
dbp:smiles	FCc1ccNC[C@@H]3[C@]2C (en)
dbp:stdinchi	1 (xsd:integer)
dbp:stdinchikey	JWJOTENAMICLJG-QWBYCMEYSA-N (en)
dbp:synonyms	GG-745; GI-198745; GI-198745X; N-[2,5-Bisphenyl]-3-oxo-4-aza-5α-androst-1-ene-17β-carboxamide (en)
dbp:tradename	Avodart, others (en)
dbp:unii	O0J6XJN02I (en)
dbp:verifiedfields	verified (en)
dbp:verifiedrevid	461091686 (xsd:integer)
dbp:watchedfields	verified (en)
dbp:width	250 (xsd:integer)
dbp:wikiPageUsesTemplate	dbt:Drugs_used_in_benign_prostatic_hypertrophy dbt:Other_dermatological_preparations dbt:Androgens_and_antiandrogens dbt:Abbrlink dbt:Authority_control dbt:Cascite dbt:Chemspidercite dbt:Cite_journal dbt:Cs1_config dbt:Drugbankcite dbt:Drugs.com dbt:Ebicite dbt:Fdacite dbt:IPAc-en dbt:Infobox_drug dbt:Keggcite dbt:Nbsp dbt:Portal_bar dbt:Refbegin dbt:Refend dbt:Reflist dbt:Respell dbt:See_also dbt:Short_description dbt:Stdinchicite dbt:Use_dmy_dates dbt:GlaxoSmithKline
dct:subject	dbc:Carboxamides dbc:Trifluoromethyl_compounds dbc:5α-Reductase_inhibitors dbc:Diketones dbc:Hair_removal dbc:Wikipedia_medicine_articles_ready_to_translate dbc:Lactams dbc:Drugs_developed_by_GSK_plc dbc:Hormonal_antineoplastic_drugs dbc:Teratogens dbc:Hair_loss_medications dbc:Prostate_cancer dbc:Androstanes
gold:hypernym	dbr:Inhibitor
rdf:type	owl:Thing dul:ChemicalObject wikidata:Q8386 dbo:ChemicalSubstance dbo:ChemicalSubstance dbo:Drug dbo:Drug dbo:Drug umbel-rc:DrugProduct
rdfs:label	Dutasteride (en) دوتاستيرايد (ar) Dutasterid (de) Dutasterida (es) Dutasterid (in) Dutasteride (it) デュタステリド (ja) Dutasteryd (pl) Dutasteride (nl) Дутастерид (uk)
rdfs:seeAlso	dbr:List_of_5α-reductase_inhibitors
owl:sameAs	http://www4.wiwiss.fu-berlin.de/sider/resource/drugs/152945 freebase:Dutasteride yago-res:Dutasteride http://www4.wiwiss.fu-berlin.de/drugbank/resource/drugs/DB01126 wikidata:Dutasteride dbpedia-de:Dutasteride dbpedia-es:Dutasteride dbpedia-it:Dutasteride dbpedia-nl:Dutasteride dbpedia-pl:Dutasteride dbpedia-tr:Dutasteride dbpedia-ja:Dutasteride dbpedia-vi:Dutasteride dbpedia-id:Dutasteride dbpedia-ar:Dutasteride dbpedia-cy:Dutasteride dbpedia-fa:Dutasteride dbpedia-fi:Dutasteride dbpedia-or:Dutasteride dbpedia-sh:Dutasteride dbpedia-sr:Dutasteride dbpedia-uk:Dutasteride dbpedia-global:Dutasteride
prov:wasDerivedFrom	wikipedia-en:Dutasteride?oldid=1310766830&ns=0
foaf:depiction	wiki-commons:Special:FilePath/Avodart.jpg wiki-commons:Special:FilePath/Dutasteride.svg
foaf:isPrimaryTopicOf	wikipedia-en:Dutasteride
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