The 2021–22 Mercer Bears men's basketball team represented Mercer University in the 2021–22 NCAA Division I men's basketball season. The Bears, led by third-year head coach Greg Gary, played their home games at Hawkins Arena in Macon, Georgia as a member of the Southern Conference. They finished the season 16–17, 8–10 in SoCon play to finish in seventh place. They defeated Western Carolina in the first round of the SoCon tournament before losing to Furman in the quarterfinals.