The 2021–22 UNC Greensboro Spartans men's basketball team represented the University of North Carolina at Greensboro during the 2021–22 NCAA Division I men's basketball season. The Spartans, led by first-year head coach Mike Jones, played their home games at the Greensboro Coliseum and Fleming Gymnasium in Greensboro, North Carolina as members of the Southern Conference (SoCon). They finished the season 17–14, 9–9 in SoCon play to finish in a tie for fifth place. As the No. 6 seed in the SoCon tournament, they lost to Samford in the quarterfinals. Guard De'Monte Buckingham was named to the Southern Conference Sports Media Association third team. They accepted an invitation to play in the 2022 College Basketball Invitational tournament where, as a No. 7 seed, they lost to No. 10-seeded Bost