The 2021–22 Illinois State Redbirds men's basketball team represented Illinois State University during the 2021–22 NCAA Division I men's basketball season. The Redbirds played their home games at Doug Collins Court at Redbird Arena in Normal, Illinois as members of the Missouri Valley Conference. The team finished the season 13–20, 5–13 in MVC play to finish in eighth place. They defeated Indiana State in the first round of the MVC tournament before losing to Northern Iowa in the quarterfinals.