About: Somatic evolution in cancer

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Somatic evolution is the accumulation of mutations and epimutations in somatic cells (the cells of a body, as opposed to germ plasm and stem cells) during a lifetime, and the effects of those mutations and epimutations on the fitness of those cells. This evolutionary process has first been shown by the studies of Bert Vogelstein in colon cancer. Somatic evolution is important in the process of aging as well as the development of some diseases, including cancer.

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  • يتجلى التطور الجسدي في تراكم الطفرات وفوق الطفرات في الخلايا الجسدية (خلايا الجسم، على عكس البلازما الجرثومية والخلايا الجذعية) خلال فترة الحياة، وتأثيراتها في صلاحية تلك الخلايا. عُرضت هذه العملية التطورية لأول مرة في دراسات برت فوغلشتاين حول سرطان القولون. إن التطور الجسدي مهم في عملية الشيخوخة وتطور بعض الأمراض، مثل السرطان. (ar)
  • Somatic evolution is the accumulation of mutations and epimutations in somatic cells (the cells of a body, as opposed to germ plasm and stem cells) during a lifetime, and the effects of those mutations and epimutations on the fitness of those cells. This evolutionary process has first been shown by the studies of Bert Vogelstein in colon cancer. Somatic evolution is important in the process of aging as well as the development of some diseases, including cancer. (en)
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  • يتجلى التطور الجسدي في تراكم الطفرات وفوق الطفرات في الخلايا الجسدية (خلايا الجسم، على عكس البلازما الجرثومية والخلايا الجذعية) خلال فترة الحياة، وتأثيراتها في صلاحية تلك الخلايا. عُرضت هذه العملية التطورية لأول مرة في دراسات برت فوغلشتاين حول سرطان القولون. إن التطور الجسدي مهم في عملية الشيخوخة وتطور بعض الأمراض، مثل السرطان. (ar)
  • Somatic evolution is the accumulation of mutations and epimutations in somatic cells (the cells of a body, as opposed to germ plasm and stem cells) during a lifetime, and the effects of those mutations and epimutations on the fitness of those cells. This evolutionary process has first been shown by the studies of Bert Vogelstein in colon cancer. Somatic evolution is important in the process of aging as well as the development of some diseases, including cancer. (en)
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  • التطور الجسدي في السرطان (ar)
  • Somatic evolution in cancer (en)
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