This HTML5 document contains 194 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
dctermshttp://purl.org/dc/terms/
dbohttp://dbpedia.org/ontology/
n17http://dbpedia.org/resource/File:
foafhttp://xmlns.com/foaf/0.1/
n10https://global.dbpedia.org/id/
dbthttp://dbpedia.org/resource/Template:
rdfshttp://www.w3.org/2000/01/rdf-schema#
freebasehttp://rdf.freebase.com/ns/
n13http://commons.wikimedia.org/wiki/Special:FilePath/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
owlhttp://www.w3.org/2002/07/owl#
wikipedia-enhttp://en.wikipedia.org/wiki/
dbphttp://dbpedia.org/property/
provhttp://www.w3.org/ns/prov#
dbchttp://dbpedia.org/resource/Category:
xsdhhttp://www.w3.org/2001/XMLSchema#
wikidatahttp://www.wikidata.org/entity/
dbrhttp://dbpedia.org/resource/

Statements

Subject Item
dbr:Epigenetics_in_insects
dbo:wikiPageWikiLink
dbr:Epigenetics_in_learning_and_memory
Subject Item
dbr:Epigenetics_in_learning_and_memory
rdfs:label
Epigenetics in learning and memory
rdfs:comment
While the cellular and molecular mechanisms of learning and memory have long been a central focus of neuroscience, it is only in recent years that attention has turned to the epigenetic mechanisms behind the dynamic changes in gene transcription responsible for memory formation and maintenance. Epigenetic gene regulation often involves the physical marking (chemical modification) of DNA or associated proteins to cause or allow long-lasting changes in gene activity. Epigenetic mechanisms such as DNA methylation and histone modifications (methylation, acetylation, and deacetylation) have been shown to play an important role in learning and memory.
foaf:depiction
n13:Initiation_of_DNA_demethylation_at_a_CpG_site.svg n13:Demethylation_of_5-methylcytosine.svg n13:Regulatory_sequence_in_a_promoter_at_a_transcription_start_site_with_a_paused_RNA_polymerase_and_a_TOP2B-induced_double-strand_break.jpg n13:HDACs'_role.jpg n13:Brain_regions_in_memory_formation_updated.jpg
dcterms:subject
dbc:Neuroscience_of_memory dbc:Learning dbc:Epigenetics
dbo:wikiPageID
35812169
dbo:wikiPageRevisionID
1122095021
dbo:wikiPageWikiLink
dbr:HDAC_inhibitor dbr:Deacetylation dbr:Taste dbr:HDAC2 dbr:Endogeny_(biology) dbr:Regulatory_sequence dbr:Entorhinal_cortex dbr:Neuroplasticity dbr:Chromatin_remodeling dbr:CpG_binding_protein_2 dbr:Medial_prefrontal_cortex dbr:Aversive_stimulus dbr:Mediator_(coactivator) dbr:Oxoguanine_glycosylase dbr:Cytosine dbr:Histone_methylation dbr:Histone_acetylation_and_deacetylation dbr:CoREST dbr:Morris_water_maze_test dbr:Histone dbr:Transcriptional_silencing dbr:Nr4a1 dbr:BDNF dbr:Acetyl_CoA dbr:Lysine dbr:Long-term_potentiation dbr:Chromatin_structure dbr:Niemann-Pick_disease,_type_C dbr:Gene_transcription dbr:Morris_water_navigation_task dbr:Spinal_muscular_atrophy dbr:Transcription_preinitiation_complex dbr:Differentially_methylated_regions dbr:Zebularine dbr:Memory_suppression dbr:Acetylation dbr:Zif268 dbr:CAMP_response_element-binding_protein dbr:Huntington's_disease dbr:Gene_expression dbr:Spatial_memory dbr:NMDA_receptor dbr:DNMT3a dbr:DNMT3b dbr:Histone_acetyltransferase dbr:GADD45 dbr:Histone_deacetylase dbr:DNMT3B dbr:P300-CBP_coactivator_family dbr:DNA_repair dbr:DNMT1 dbr:DNMT3A dbr:Nucleosome dbr:Spinal_and_bulbar_muscular_atrophy dbr:Extracellular_signal-regulated_kinases dbr:Histone_H4 dbr:Synaptic_plasticity dbr:Epigenetic_gene_regulation dbr:Amino_acid dbr:Histone_H3 dbr:Central_nervous_system dbr:G9a-like_protein dbr:Gene dbr:Acetyl_group dbr:Friedreich's_ataxia dbr:DNA_demethylation dbr:Dorsal_hippocampus dbr:G9a dbr:Egr1 dbr:Reelin dbr:8-oxo-2'-deoxyguanosine dbc:Neuroscience_of_memory dbr:Synaptogenesis dbr:Fear_conditioning dbr:Transcription_factor dbr:Post-traumatic_stress_disorder dbr:ERK_pathway dbr:Toluene dbr:Epigenetics dbr:Amyotrophic_lateral_sclerosis dbr:Object_location_test n17:Initiation_of_DNA_demethylation_at_a_CpG_site.svg dbr:Rett_syndrome dbr:CREB dbc:Learning dbr:Brain-derived_neurotrophic_factor dbr:CREB-binding_protein dbr:C-Fos dbr:Brain dbr:Neuroscience dbr:Memory_consolidation dbr:DNA_methyltransferase dbr:Memory dbr:Knock_out_mice dbr:MAPK dbr:NMDA dbr:DNA_methylation dbr:GABAergic dbr:Encoding_(memory) dbr:Prefrontal_cortex dbr:Reactive_oxygen_species dbr:Non-homologous_end_joining dbr:Long-term_memories dbr:Methyltransferase dbr:DNA_oxidation dbr:Sodium_butyrate n17:HDACs'_role.jpg dbr:Enhancer_(genetics) n17:Regulatory_sequence_in_a_promoter_at_a_transcription_start_site_with_a_paused_RNA_polymerase_and_a_TOP2B-induced_double-strand_break.jpg dbr:Promoter_(biology) n17:Brain_regions_in_memory_formation_updated.jpg dbr:Granule_cell dbr:Promoter_(genetics) dbr:5-hydroxymethylcytosine dbr:DNA dbr:GLUR1 dbr:Hippocampus dbr:Insular_cortex dbr:Dentatorubropallidoluysian_atrophy dbr:Base_excision_repair dbr:Tet_methylcytosine_dioxygenase_1 dbr:Immediate_early_gene dbr:CpG_sites dbr:Protein_phosphatase_1 dbr:DNMT_inhibitor dbr:Transcription_(biology) dbr:Cornu_Ammonis_area_1 dbr:Transcription_(genetics) dbr:Suberoylanilide_hydroxamic_acid dbr:CpG_island dbr:Dentate_gyrus dbr:CpG_site dbr:Methylation dbr:Alzheimer's_disease dbr:HDAC3 dbr:HDAC4 n17:Demethylation_of_5-methylcytosine.svg dbr:RGFP136 dbr:Long_term_potentiation dbr:HDAC1 dbr:Thymine-DNA_glycosylase dbr:MRNA dbr:5-methylcytosine dbr:Trichostatin_A dbr:Learning dbc:Epigenetics dbr:CREB_binding_protein dbr:TET_enzymes dbr:Nr4a2 dbr:Bdnf dbr:Rubinstein-Tabyi_syndrome dbr:5-aza-2′-deoxycytidine dbr:Schizophrenia dbr:TOP2B dbr:Spinocerebellar_ataxia dbr:Long-term_memory dbr:MLL_(gene) dbr:Long-term_depression
owl:sameAs
n10:4ju9C freebase:m.0jt3vw5 wikidata:Q5382901
dbp:wikiPageUsesTemplate
dbt:Short_description dbt:Reflist dbt:Clear dbt:Which
dbo:thumbnail
n13:HDACs'_role.jpg?width=300
dbo:abstract
While the cellular and molecular mechanisms of learning and memory have long been a central focus of neuroscience, it is only in recent years that attention has turned to the epigenetic mechanisms behind the dynamic changes in gene transcription responsible for memory formation and maintenance. Epigenetic gene regulation often involves the physical marking (chemical modification) of DNA or associated proteins to cause or allow long-lasting changes in gene activity. Epigenetic mechanisms such as DNA methylation and histone modifications (methylation, acetylation, and deacetylation) have been shown to play an important role in learning and memory.
prov:wasDerivedFrom
wikipedia-en:Epigenetics_in_learning_and_memory?oldid=1122095021&ns=0
dbo:wikiPageLength
52825
foaf:isPrimaryTopicOf
wikipedia-en:Epigenetics_in_learning_and_memory
Subject Item
dbr:DNA_damage_(naturally_occurring)
dbo:wikiPageWikiLink
dbr:Epigenetics_in_learning_and_memory
Subject Item
dbr:GADD45G
dbo:wikiPageWikiLink
dbr:Epigenetics_in_learning_and_memory
Subject Item
dbr:Memory
dbo:wikiPageWikiLink
dbr:Epigenetics_in_learning_and_memory
Subject Item
dbr:Long-term_memory
dbo:wikiPageWikiLink
dbr:Epigenetics_in_learning_and_memory
Subject Item
dbr:5-Hydroxymethylcytosine
dbo:wikiPageWikiLink
dbr:Epigenetics_in_learning_and_memory
Subject Item
dbr:8-Oxo-2'-deoxyguanosine
dbo:wikiPageWikiLink
dbr:Epigenetics_in_learning_and_memory
Subject Item
dbr:Hippocampus
dbo:wikiPageWikiLink
dbr:Epigenetics_in_learning_and_memory
Subject Item
dbr:Transcription_factor
dbo:wikiPageWikiLink
dbr:Epigenetics_in_learning_and_memory
Subject Item
dbr:TET_enzymes
dbo:wikiPageWikiLink
dbr:Epigenetics_in_learning_and_memory
Subject Item
dbr:Reactive_oxygen_species
dbo:wikiPageWikiLink
dbr:Epigenetics_in_learning_and_memory
Subject Item
wikipedia-en:Epigenetics_in_learning_and_memory
foaf:primaryTopic
dbr:Epigenetics_in_learning_and_memory