About: Deferiprone

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Deferiprone, sold under the brand name Ferriprox among others, is a medication that chelates iron and is used to treat iron overload in thalassaemia major. It was first approved and indicated for use in treating thalassaemia major in 1994 and had been licensed for use in the European Union for many years while awaiting approval in Canada and in the United States. On October 14, 2011, it was approved for use in the US under the FDA's accelerated approval program.

Property Value
dbo:abstract
  • ديفيريبرون هو دواء يتمخلب بالحديد ويستعمل في علاج التحميل المفرط للحديد في الثلاسيمية الكبرى. رخص استعماله أول مرة في علاج الثلاسيمية الكبرى في عام 1994 وقد حصل على الترخيص أولا في أوروبا وآسيا لكنه انتظر سنوات عديدة قبل ترخيصه في كندا والولايات المتحدة. ففي 14 أكتوبر 2011, حصل على موافقة في الولايات المتحدة تحت لإدارة الغذاء والدواء. (ar)
  • Deferiprone, sold under the brand name Ferriprox among others, is a medication that chelates iron and is used to treat iron overload in thalassaemia major. It was first approved and indicated for use in treating thalassaemia major in 1994 and had been licensed for use in the European Union for many years while awaiting approval in Canada and in the United States. On October 14, 2011, it was approved for use in the US under the FDA's accelerated approval program. The most common side effects include red-brown urine (showing that iron is being removed through the urine), nausea (feeling sick), abdominal pain (stomach ache) and vomiting. Less common but more serious side effects are agranulocytosis (very low levels of granulocytes, a type of white blood cell) and neutropenia (low levels of neutrophils, a type of white blood cell that fights infections). (en)
  • Le défériprone est une molécule chélatrice du fer, utilisé comme médicament dans les surcharges en fer. (fr)
  • Il deferiprone è un principio attivo che agisce come ferrochelante; esso è indicato secondo l'RCP nel trattamento dell'accumulo di ferro (emosiderosi) nei pazienti affetti da talassemia maggiore, quando la terapia con deferoxamina è controindicata o non adeguata. Il farmaco è stato studiato dalla ApoPharma. In Italia è commercializzato dalla Chiesi Farmaceutici dal 1999, con il nome: Ferriprox. (it)
  • Deferypron (łac. Deferipronum) – związek chelatujący żelazo, stosowany w leczeniu talasemii. (pl)
  • Deferiprona, também conhecido pelo nome comercial Ferriprox, é um fármaco usado como agente quelante do ferro. É usado no tratamento de talassemia. A deferiprona é um tratamento alternativo para a sobrecarga de ferro em pacientes com talassemia major incapazes de receber a desferroxamina. (pt)
dbo:alternativeName
  • Ferriprox (en)
dbo:casNumber
  • 30652-11-0
dbo:chEBI
  • 68554
dbo:chEMBL
  • 70927
dbo:drugbank
  • DB08826
dbo:fdaUniiCode
  • 2BTY8KH53L
dbo:kegg
  • D07416
dbo:medlinePlus
  • a612016
dbo:pubchem
  • 2972
dbo:thumbnail
dbo:wikiPageExternalLink
dbo:wikiPageID
  • 9494348 (xsd:integer)
dbo:wikiPageLength
  • 10209 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1105534631 (xsd:integer)
dbo:wikiPageWikiLink
dbp:atcPrefix
  • V03 (en)
dbp:atcSuffix
  • AC02 (en)
dbp:c
  • 7 (xsd:integer)
dbp:casNumber
  • 30652 (xsd:integer)
dbp:chebi
  • 68554 (xsd:integer)
dbp:chembl
  • 70927 (xsd:integer)
dbp:chemspiderid
  • 2866 (xsd:integer)
dbp:dailymedid
  • Deferiprone (en)
dbp:drugbank
  • DB08826 (en)
dbp:eliminationHalfLife
  • 10800.0
dbp:excretion
dbp:h
  • 9 (xsd:integer)
dbp:iupacName
  • 3 (xsd:integer)
dbp:iupharLigand
  • 7456 (xsd:integer)
dbp:kegg
  • D07416 (en)
dbp:legalAu
  • S4 (en)
dbp:legalEu
  • Rx-only (en)
dbp:legalStatus
  • Rx-only (en)
dbp:legalUk
  • POM (en)
dbp:legalUkComment
  • / P (en)
dbp:legalUs
  • Rx-only (en)
dbp:licenceEu
  • yes (en)
dbp:licenceUs
  • Deferiprone (en)
dbp:medlineplus
  • a612016 (en)
dbp:metabolism
dbp:n
  • 1 (xsd:integer)
dbp:o
  • 2 (xsd:integer)
dbp:pregnancyAu
  • D (en)
dbp:pregnancyUs
  • D (en)
dbp:pubchem
  • 2972 (xsd:integer)
dbp:routesOfAdministration
dbp:smiles
  • O=C\1C=CC (en)
dbp:stdinchi
  • 1 (xsd:integer)
dbp:stdinchikey
  • TZXKOCQBRNJULO-UHFFFAOYSA-N (en)
dbp:tradename
  • Ferriprox (en)
dbp:unii
  • 2 (xsd:integer)
dbp:verifiedfields
  • changed (en)
dbp:verifiedrevid
  • 443270530 (xsd:integer)
dbp:watchedfields
  • changed (en)
dbp:width
  • 120 (xsd:integer)
dbp:wikiPageUsesTemplate
dcterms:subject
gold:hypernym
rdf:type
rdfs:comment
  • ديفيريبرون هو دواء يتمخلب بالحديد ويستعمل في علاج التحميل المفرط للحديد في الثلاسيمية الكبرى. رخص استعماله أول مرة في علاج الثلاسيمية الكبرى في عام 1994 وقد حصل على الترخيص أولا في أوروبا وآسيا لكنه انتظر سنوات عديدة قبل ترخيصه في كندا والولايات المتحدة. ففي 14 أكتوبر 2011, حصل على موافقة في الولايات المتحدة تحت لإدارة الغذاء والدواء. (ar)
  • Le défériprone est une molécule chélatrice du fer, utilisé comme médicament dans les surcharges en fer. (fr)
  • Il deferiprone è un principio attivo che agisce come ferrochelante; esso è indicato secondo l'RCP nel trattamento dell'accumulo di ferro (emosiderosi) nei pazienti affetti da talassemia maggiore, quando la terapia con deferoxamina è controindicata o non adeguata. Il farmaco è stato studiato dalla ApoPharma. In Italia è commercializzato dalla Chiesi Farmaceutici dal 1999, con il nome: Ferriprox. (it)
  • Deferypron (łac. Deferipronum) – związek chelatujący żelazo, stosowany w leczeniu talasemii. (pl)
  • Deferiprona, também conhecido pelo nome comercial Ferriprox, é um fármaco usado como agente quelante do ferro. É usado no tratamento de talassemia. A deferiprona é um tratamento alternativo para a sobrecarga de ferro em pacientes com talassemia major incapazes de receber a desferroxamina. (pt)
  • Deferiprone, sold under the brand name Ferriprox among others, is a medication that chelates iron and is used to treat iron overload in thalassaemia major. It was first approved and indicated for use in treating thalassaemia major in 1994 and had been licensed for use in the European Union for many years while awaiting approval in Canada and in the United States. On October 14, 2011, it was approved for use in the US under the FDA's accelerated approval program. (en)
rdfs:label
  • Deferiprone (en)
  • ديفيريبرون (ar)
  • Défériprone (fr)
  • Deferiprone (it)
  • Deferypron (pl)
  • Deferiprona (pt)
owl:sameAs
prov:wasDerivedFrom
foaf:depiction
foaf:isPrimaryTopicOf
is dbo:wikiPageRedirects of
is dbo:wikiPageWikiLink of
is foaf:primaryTopic of
Powered by OpenLink Virtuoso    This material is Open Knowledge     W3C Semantic Web Technology     This material is Open Knowledge    Valid XHTML + RDFa
This content was extracted from Wikipedia and is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License