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Bēltu-ša-Rēš was a Mesopotamian goddess associated with a temple, or temples, bearing the name Rēš. She is only attested in sources from Uruk from the Neo-Babylonian and Seleucid periods. In the former, she belonged to the pentad of main deities of the city alongside Ishtar, Nanaya, Uṣur-amāssu and Urkayītu. In the latter, she served as the protective deity of a new temple complex dedicated to Anu and Antu.