Santo Domingo Church, formally known as the National Shrine of Our Lady of the Most Holy Rosary (Spanish: Santuario Nacional de Nuestra Señora del Santísimo Rosario; Filipino: Pambansang Dambana ng Mahal na Birhen ng Santo Rosaryo), is the largest church in Metro Manila and one of the biggest churches in Asia. It is dedicated to Mary, mother of Jesus under her title Our Lady of the Most Holy Rosary.