About: TANGO2

Property	Value
dbo:abstract	Transport and golgi organization 2 homolog (TANGO2) also known as chromosome 22 open reading frame 25 (C22orf25) is a protein that in humans is encoded by the TANGO2 gene. The function of C22orf25 is not currently known. It is characterized by the NRDE superfamily domain (DUF883), which is strictly known for the conserved amino acid sequence of (N)-Asparagine (R)-Arginine (D)-Aspartic Acid (E)-Glutamic Acid. This domain is found among distantly related species from the six kingdoms: Eubacteria, Archaebacteria, Protista, Fungi, Plantae, and Animalia and is known to be involved in Golgi organization and protein secretion. It is likely that it localizes in the cytoplasm but is anchored in the cell membrane by the second amino acid. C22orf25 is also xenologous to T10 like proteins in the Fowlpox Virus and Canarypox Virus. The gene coding for C22orf25 is located on chromosome 22 and the location q11.21, so it is often associated with 22q11.2 deletion syndrome. (en) TANGO2 (англ. Transport and golgi organization 2 homolog) – білок, який кодується однойменним геном, розташованим у людей на короткому плечі 22-ї хромосоми. Довжина поліпептидного ланцюга білка становить 276 амінокислот, а молекулярна маса — 30 937. Послідовність амінокислот A: АланінC: ЦистеїнD: Аспарагінова кислотаE: Глутамінова кислотаF: ФенілаланінG: ГліцинH: ГістидинI: ІзолейцинK: ЛізинL: ЛейцинM: МетіонінN: АспарагінP: ПролінQ: ГлутамінR: АргінінS: СеринT: ТреонінV: ВалінW: Триптофан Y: Тирозин Задіяний у такому біологічному процесі, як альтернативний сплайсинг. Локалізований у апараті гольджі. (uk)
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dbo:wikiPageExternalLink	http://tango2research.org https://www.tango2.it https://www.ncbi.nlm.nih.gov/protein/ACG35095 https://www.ncbi.nlm.nih.gov/protein/BAK62258.1 https://www.ncbi.nlm.nih.gov/protein/CBQ69093 https://www.ncbi.nlm.nih.gov/protein/NP_001003781 https://www.ncbi.nlm.nih.gov/protein/NP_001004885.1 https://www.ncbi.nlm.nih.gov/protein/NP_001007837 https://www.ncbi.nlm.nih.gov/protein/NP_001083694 https://www.ncbi.nlm.nih.gov/protein/NP_001167100 https://www.ncbi.nlm.nih.gov/protein/NP_039033 https://www.ncbi.nlm.nih.gov/protein/NP_613049.2 https://www.ncbi.nlm.nih.gov/protein/NP_690870.3 https://www.ncbi.nlm.nih.gov/protein/NP_955117 https://www.ncbi.nlm.nih.gov/protein/XP_001010229 https://www.ncbi.nlm.nih.gov/protein/XP_001781807 https://www.ncbi.nlm.nih.gov/protein/XP_002787624 https://www.ncbi.nlm.nih.gov/protein/XP_002920626 https://www.ncbi.nlm.nih.gov/protein/XP_003210928 https://www.ncbi.nlm.nih.gov/protein/XP_003236126 https://www.ncbi.nlm.nih.gov/protein/YP_002005507.1 https://www.ncbi.nlm.nih.gov/protein/YP_003481665 https://www.ncbi.nlm.nih.gov/protein/YP_004597780.1 https://www.ncbi.nlm.nih.gov/protein/YP_004977059
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rdfs:comment	Transport and golgi organization 2 homolog (TANGO2) also known as chromosome 22 open reading frame 25 (C22orf25) is a protein that in humans is encoded by the TANGO2 gene. The function of C22orf25 is not currently known. It is characterized by the NRDE superfamily domain (DUF883), which is strictly known for the conserved amino acid sequence of (N)-Asparagine (R)-Arginine (D)-Aspartic Acid (E)-Glutamic Acid. This domain is found among distantly related species from the six kingdoms: Eubacteria, Archaebacteria, Protista, Fungi, Plantae, and Animalia and is known to be involved in Golgi organization and protein secretion. It is likely that it localizes in the cytoplasm but is anchored in the cell membrane by the second amino acid. C22orf25 is also xenologous to T10 like proteins in the Fowlp (en) TANGO2 (англ. Transport and golgi organization 2 homolog) – білок, який кодується однойменним геном, розташованим у людей на короткому плечі 22-ї хромосоми. Довжина поліпептидного ланцюга білка становить 276 амінокислот, а молекулярна маса — 30 937. Послідовність амінокислот A: АланінC: ЦистеїнD: Аспарагінова кислотаE: Глутамінова кислотаF: ФенілаланінG: ГліцинH: ГістидинI: ІзолейцинK: ЛізинL: ЛейцинM: МетіонінN: АспарагінP: ПролінQ: ГлутамінR: АргінінS: СеринT: ТреонінV: ВалінW: Триптофан Y: Тирозин (uk)
rdfs:label	TANGO2 (en) TANGO2 (uk)
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