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An overwhelming post-splenectomy infection (OPSI) is a rare but rapidly fatal infection occurring in individuals following removal (or permanent dysfunction) of the spleen. The infections are typically characterized by either meningitis or sepsis, and are caused by encapsulated organisms including Streptococcus pneumoniae. It is a medical emergency and requires immediate treatment. Death has been reported to occur within 12 hours.

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dbo:abstract
  • Das Postsplenektomie-Syndrom (OPSI-Syndrom, engl. overwhelming postsplenectomy infection syndrome) ist eine besonders schwere Verlaufsform einer bakteriellen Infektion nach einer operativen Entfernung der Milz (Splenektomie). (de)
  • An overwhelming post-splenectomy infection (OPSI) is a rare but rapidly fatal infection occurring in individuals following removal (or permanent dysfunction) of the spleen. The infections are typically characterized by either meningitis or sepsis, and are caused by encapsulated organisms including Streptococcus pneumoniae. It is a medical emergency and requires immediate treatment. Death has been reported to occur within 12 hours. The spleen is necessary for protection against encapsulated bacteria (see Mechanism) and as such when removed by splenectomy it can lead to rapid unchallenged infection by encapsulated bacteria. The rapid progression from mild viral symptoms to sepsis is one of the things that makes OPSI particularly dangerous. Another source of infection are species of Babesia, which are tick-borne parasites that cause babesiosis. Infection with Capnocytophaga canimorsus after dog bites can also cause the condition. (en)
  • Posocznica posplenektomijna in. zespół OPSI (ang. overwhelming post-splenectomy infection (OPSI), overwhelming post-splenectomy sepsis (OPSS)) – posocznica o piorunującym przebiegu występująca u pacjentów z asplenią (faktyczny lub funkcjonalny brak śledziony). (pl)
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dbp:causes
  • Exposure to pathogens following splenectomy or asplenia (en)
dbp:name
  • Overwhelming post-splenectomy infection (en)
dbp:onset
  • 172800.0
dbp:prognosis
  • Up to 99% mortality rate (en)
dbp:risks
  • 9.46728E7
dbp:specialty
dbp:synonym
  • Overwhelming post-splenectomy sepsis (en)
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rdfs:comment
  • Das Postsplenektomie-Syndrom (OPSI-Syndrom, engl. overwhelming postsplenectomy infection syndrome) ist eine besonders schwere Verlaufsform einer bakteriellen Infektion nach einer operativen Entfernung der Milz (Splenektomie). (de)
  • Posocznica posplenektomijna in. zespół OPSI (ang. overwhelming post-splenectomy infection (OPSI), overwhelming post-splenectomy sepsis (OPSS)) – posocznica o piorunującym przebiegu występująca u pacjentów z asplenią (faktyczny lub funkcjonalny brak śledziony). (pl)
  • An overwhelming post-splenectomy infection (OPSI) is a rare but rapidly fatal infection occurring in individuals following removal (or permanent dysfunction) of the spleen. The infections are typically characterized by either meningitis or sepsis, and are caused by encapsulated organisms including Streptococcus pneumoniae. It is a medical emergency and requires immediate treatment. Death has been reported to occur within 12 hours. (en)
rdfs:label
  • Postsplenektomie-Syndrom (de)
  • Overwhelming post-splenectomy infection (en)
  • Posocznica posplenektomijna (pl)
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