The Northeast Conference on Science and Skepticism (NECSS, pronounced as "nexus") is a four-day conference focusing on science and skepticism founded in 2009 and held annually in New York City. NECSS is jointly run by the New York City Skeptics (NYCS) and the New England Skeptical Society (NESS). The Society for Science-Based Medicine joined as a full sponsor of the conference in 2015. As of 2016, attendance was estimated at approximately 500 people.