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Formylglycine-generating enzyme (FGE), located at 3p26.1 in humans, is the name for an enzyme present in the endoplasmic reticulum that catalyzes the conversion of cysteine to formylglycine (fGly). There are two main classes of FGE, aerobic and anaerobic. FGE activates sulfatases, which are essential for the degradation of sulfate esters. The catalytic activity of sulfatases is dependent upon a formylglycine (sometimes called oxoalanine) residue in the active site.

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  • L'enzim generador de formilglicina (FGE de Formylglycine-generating enzyme) és el nom d'un enzim que catalitza la conversió de cisteïna en formilglicina (fGly). Hi ha dues classes principals d'FGE, aeròbic i anaeròbic. L'FGE activa les sulfatases, que són essencials per a la degradació dels èsters sulfatats. L'activitat catalítica de les sulfatases depèn d'un residu de formilglicina (de vegades anomenat oxoalanina) a la zona activa. (ca)
  • Formylglycin-generierendes Enzym (FGE) ist ein Enzym aus der Gruppe der Oxygenasen. Es verändert posttranslational ein Cystein in Sulfatasen in ein Formylglycin. FGE kann sowohl in Pro- als auch in Eukaryoten vorkommen. (de)
  • Formylglycine-generating enzyme (FGE), located at 3p26.1 in humans, is the name for an enzyme present in the endoplasmic reticulum that catalyzes the conversion of cysteine to formylglycine (fGly). There are two main classes of FGE, aerobic and anaerobic. FGE activates sulfatases, which are essential for the degradation of sulfate esters. The catalytic activity of sulfatases is dependent upon a formylglycine (sometimes called oxoalanine) residue in the active site. (en)
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  • 1.8.99
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  • 336.0
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  • 1.800000 (xsd:double)
dbp:interpro
  • IPR005532 (en)
dbp:name
  • Formylglycine-generating enzyme (en)
dbp:pfam
  • PF03781 (en)
dbp:symbol
  • FGE-sulfatase (en)
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  • L'enzim generador de formilglicina (FGE de Formylglycine-generating enzyme) és el nom d'un enzim que catalitza la conversió de cisteïna en formilglicina (fGly). Hi ha dues classes principals d'FGE, aeròbic i anaeròbic. L'FGE activa les sulfatases, que són essencials per a la degradació dels èsters sulfatats. L'activitat catalítica de les sulfatases depèn d'un residu de formilglicina (de vegades anomenat oxoalanina) a la zona activa. (ca)
  • Formylglycin-generierendes Enzym (FGE) ist ein Enzym aus der Gruppe der Oxygenasen. Es verändert posttranslational ein Cystein in Sulfatasen in ein Formylglycin. FGE kann sowohl in Pro- als auch in Eukaryoten vorkommen. (de)
  • Formylglycine-generating enzyme (FGE), located at 3p26.1 in humans, is the name for an enzyme present in the endoplasmic reticulum that catalyzes the conversion of cysteine to formylglycine (fGly). There are two main classes of FGE, aerobic and anaerobic. FGE activates sulfatases, which are essential for the degradation of sulfate esters. The catalytic activity of sulfatases is dependent upon a formylglycine (sometimes called oxoalanine) residue in the active site. (en)
rdfs:label
  • Enzim generador de formilglicina (ca)
  • Formylglycin-generierendes Enzym (de)
  • Formylglycine-generating enzyme (en)
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  • Formylglycine-generating enzyme (en)
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