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- Sir Ernest Laurence Kennaway (* 23. Mai 1881 in Exeter; † 1. Januar 1958 in London) war ein britischer Mediziner (Pathologie). Kennaway studierte Naturwissenschaften am University College London (UCL) und ab 1898 an der Universität Oxford (New College) mit dem B.A. 1903 und Medizin am Middlesex Hospital mit dem B.M. und B. Chir. (1907). Danach war er am Lister Institute for Preventive Medicine und am UCL bevor er 1909 wieder in Oxford war mit einer Hulme Scholarship am Brasenose College.1911 promovierte er in Oxford in Medizin (M.D.) und 1915 in am UCL in physiologischer Chemie (D.Sc.). 1909 wurde er Demonstrator für Physiologie am Guy's Hospital in London und 1914 Leiter der Abteilung chemische Pathologie am neu eröffneten Bland-Sutton Institute of Pathology. 1931 wurde er als Nachfolger von Archibald Leitch Professor für chemische Pathologie an der Universität London. 1946 wurde er emeritiert. Außerdem war er 1931 bis 1946 Direktor des Research Institute of the Cancer (später das Royal Marsden Hospital). Ab 1946 forschte er in der Abteilung Pathologie des St. Bartholomew's Hospital. Er befasste sich mit dem Purin-Stoffwechsel und Ketonurie und mit krebserzeugenden Stoffen. Er fand, dass die karzinogenen Stoffe im Steinkohlenteer zyklische Kohlenwasserstoffe sind und identifizierte eine Reihe davon. 1930 wies er nach dass polyzyklische aromatische Kohlenwasserstoffe (PAH) auf der Haut der Maus Krebs erzeugen. 1947 führte er den Anstieg von Lungenkrebs bei einer Konferenz des Medical Research Council auf Zigarettenrauch statt auch Luftverschmutzung zurück. Die Konferenz regte die Durchführung einer großangelegten Studie dazu an, was zur Studie von Austin Bradford Hill und Richard Doll von 1950 führte. 1941 wurde er Fellow der Royal Society, deren Royal Medal 1941 erhielt. 1942 wurde er Honorary Fellow des New College und 1947 wurde er geadelt und Ehrenmitglied der American Association for Cancer Research. 1954 wurde er auswärtiges Ehrenmitglied der belgischen Akademie für Medizin. 1950 erhielt er die Osier Memorial Medal und 1937 die Baly Medal. Er litt in seinen letzten 30 Jahren an der Parkinson-Krankheit. (de)
- Sir Ernest Laurence Kennaway FRS (23 May 1881 – 1 January 1958) was a British pathologist and Royal Medal winner. He first became interested in natural life when, due to a childhood illness, he was encouraged to spend time outdoors. He was trained at University College London, and in 1898 was accepted into New College, Oxford on an open scholarship to study natural sciences. He graduated with a B.A. in 1903, and after three years at Middlesex Hospital he completed a Bachelor of Medicine and Surgery. After graduating he worked for The Lister Institute for Preventive Medicine and UCL before returning to Oxford, this time to Brasenose College on a Hulme scholarship in 1909. He became a Travelling Fellow of Brasenose in 1910, a Doctor of Medicine in 1911 and a Doctor of Science (specifically physiological chemistry) in 1915. In 1909 he became a physiology demonstrator at Guy's Hospital, where he remained until he was made head of the department of chemical pathology at the Bland-Sutton Institute of Pathology in 1914. As head of department he conducted research into purine metabolism and ketonuria, proving in 1921 that the carcinogen in coal was a cyclic hydrocarbon. In 1929 he discovered the first pure compound to show evidence of cancer-causing activity, 1:2:5:6-dibenzanthracene, and also discovered a series of other carcinogenic hydrocarbons including methylcholanthrene. In 1930, Kennaway and Izrael Hieger showed for the first time that single polycyclic aromatic hydrocarbons (PAHs), such as dibenz[a,h]anthracene, are tumorigenic in mouse skin. Between 1932 and 1942 he published six articles on these discoveries in the Proceedings of the Royal Society. After the death of Professor Archibald Leitch in 1931, Kenneway became professor of chemical pathology at the University of London, where he remained until his retirement in 1946. He was awarded the Royal Medal in 1941 "For his discovery of the nature of the carcinogenic substances in coal tar and for his investigations on production of cancer by synthetic substances." and was knighted in 1947. At a conference commissioned by the Medical Research Council in 1947, he suggested that cigarette smoking rather than air pollution might be a cause of the large and continuing increase in lung cancer. The conference concluded that a large-scale case-control study should be undertaken, which led to the classic study of Doll and Hill that linked smoking to lung cancer. For over thirty years he had suffered from Parkinson's disease, and this eventually killed him on 1 January 1958. (en)
- Sir Ernest Laurence Kennaway FRS (23 mai 1881 - 1er janvier 1958) est un pathologiste britannique et lauréat de la Médaille royale. (fr)
- アーネスト・ケナウェイ（Ernest Laurence Kennaway、1881年5月23日 - 1958年1月1日）はイギリスの病理学者、医師。発ガン物質の特定を行ったことで知られる。王立協会フェロー。 (ja)
- Ernest Laurence Kennaway (Exeter, 23 de maio de 1881 — Great Missenden, 1 de janeiro de 1958) foi um patologista britânico. (pt)
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- 5348 (xsd:nonNegativeInteger)
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- Velwell Villas, Exeter (en)
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- Discovery of the first pure compound to show carcinogenic activity (en)
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- Sir Ernest Laurence Kennaway (en)
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- Sir Ernest Laurence Kennaway FRS (23 mai 1881 - 1er janvier 1958) est un pathologiste britannique et lauréat de la Médaille royale. (fr)
- アーネスト・ケナウェイ（Ernest Laurence Kennaway、1881年5月23日 - 1958年1月1日）はイギリスの病理学者、医師。発ガン物質の特定を行ったことで知られる。王立協会フェロー。 (ja)
- Ernest Laurence Kennaway (Exeter, 23 de maio de 1881 — Great Missenden, 1 de janeiro de 1958) foi um patologista britânico. (pt)
- Sir Ernest Laurence Kennaway FRS (23 May 1881 – 1 January 1958) was a British pathologist and Royal Medal winner. He first became interested in natural life when, due to a childhood illness, he was encouraged to spend time outdoors. He was trained at University College London, and in 1898 was accepted into New College, Oxford on an open scholarship to study natural sciences. He graduated with a B.A. in 1903, and after three years at Middlesex Hospital he completed a Bachelor of Medicine and Surgery. After graduating he worked for The Lister Institute for Preventive Medicine and UCL before returning to Oxford, this time to Brasenose College on a Hulme scholarship in 1909. He became a Travelling Fellow of Brasenose in 1910, a Doctor of Medicine in 1911 and a Doctor of Science (specifically p (en)
- Sir Ernest Laurence Kennaway (* 23. Mai 1881 in Exeter; † 1. Januar 1958 in London) war ein britischer Mediziner (Pathologie). Kennaway studierte Naturwissenschaften am University College London (UCL) und ab 1898 an der Universität Oxford (New College) mit dem B.A. 1903 und Medizin am Middlesex Hospital mit dem B.M. und B. Chir. (1907). Danach war er am Lister Institute for Preventive Medicine und am UCL bevor er 1909 wieder in Oxford war mit einer Hulme Scholarship am Brasenose College.1911 promovierte er in Oxford in Medizin (M.D.) und 1915 in am UCL in physiologischer Chemie (D.Sc.). 1909 wurde er Demonstrator für Physiologie am Guy's Hospital in London und 1914 Leiter der Abteilung chemische Pathologie am neu eröffneten Bland-Sutton Institute of Pathology. 1931 wurde er als Nachfolger (de)
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- Ernest Kennaway (de)
- Ernest Kennaway (fr)
- Ernest Kennaway (en)
- アーネスト・ケナウェイ (ja)
- Ernest Kennaway (pt)
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- Sir Ernest Laurence Kennaway (en)
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