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Chemotherapy-induced nausea and vomiting (CINV) is a common side-effect of many cancer treatments. Nausea and vomiting are two of the most feared cancer treatment-related side effects for cancer patients and their families. In 1983, Coates et al. found that patients receiving chemotherapy ranked nausea and vomiting as the first and second most severe side effects, respectively. Up to 20% of patients receiving highly emetogenic agents in this era postponed, or even refused, potentially curative treatments. Since the 1990s, several novel classes of antiemetics have been developed and commercialized, becoming a nearly universal standard in chemotherapy regimens, and helping to better manage these symptoms in a large portion of patients. Efficient mediation of these unpleasant and sometimes cr

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  • الغثيان والقيء الناجم عن العلاج الكيميائي (CINV) هو أثر جانبي شائع الحدوث في كثير من علاجات السرطان . يعتبر القيء والغثيان من أكثر الآثار الجانبية المرتبطة بعلاجات السرطان والتي تسبب الخوف لمرضى السرطان وعائلاتهم. ففي عام 1983 وجد كوتس وآخرون أن المرضى الذين يتلقون علاجا كيميائيا صنفوا القيء والغثيان كأولى الآثار الجانبية الأكثر شدة على التوالي. ووجد أن 20% من الذين يعانون من غثيان وقيء شديدين في العلاج يأجلون أو حتى يرفضون العلاجات الدوائية المحتمل تسببها لذلك. في التسعينات طُورت العديد من الفئات الجديدة المقاومة للغثيان تجاريا لتصبح مقياسا عالميا جديدا في نظم العلاجات الكيميائية، كما تساعد في إدارة تلك الأعراض لعدد كبير من المرضى. يؤدي هذا التدخل الفعال غير المرغوب والأعراض المدمرة أحيانا إلى زيادة جودة حياة المرضى وبالتالي فإن زيادة تحمل المرضى يؤدي لدورات علاجية أكثر فاعلية. (ar)
  • Chemotherapy-induced nausea and vomiting (CINV) is a common side-effect of many cancer treatments. Nausea and vomiting are two of the most feared cancer treatment-related side effects for cancer patients and their families. In 1983, Coates et al. found that patients receiving chemotherapy ranked nausea and vomiting as the first and second most severe side effects, respectively. Up to 20% of patients receiving highly emetogenic agents in this era postponed, or even refused, potentially curative treatments. Since the 1990s, several novel classes of antiemetics have been developed and commercialized, becoming a nearly universal standard in chemotherapy regimens, and helping to better manage these symptoms in a large portion of patients. Efficient mediation of these unpleasant and sometimes crippling symptoms results in increased quality of life for the patient, and better overall health of the patient, and, due to better patient tolerance, more effective treatment cycles. (en)
  • A náusea e vômito induzidos por quimioterapia (abreviado NVIQ, na literatura em inglês CINV, chemotherapy-induced nausea and vomiting) são um efeito colateral comum de muitos tratamentos contra o câncer. Náuseas e vômitos são dois dos efeitos colaterais relacionados ao tratamento de câncer mais temidos para pacientes com câncer e suas famílias. Em 1983, Coates et al. descobriram que os pacientes que receberam quimioterapia classificaram náuseas e vômitos como o primeiro e segundo efeitos colaterais mais graves, respectivamente. Até 20% dos pacientes que receberam agentes altamente emetogênicos nesta época adiaram, ou até mesmo recusaram, tratamentos potencialmente curativos. Desde a década de 1990, várias novas classes de antieméticos foram desenvolvidas e comercializadas, tornando-se um padrão quase universal em esquemas de quimioterapia e ajudando a gerir melhor esses sintomas em grande parte dos pacientes. A mediação eficiente desses sintomas desagradáveis e às vezes incapacitantes resulta em maior qualidade de vida para o paciente e melhor saúde geral do paciente e, devido a uma melhor tolerância ao paciente, ciclos de tratamento mais efetivos. (pt)
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  • الغثيان والقيء الناجم عن العلاج الكيميائي (CINV) هو أثر جانبي شائع الحدوث في كثير من علاجات السرطان . يعتبر القيء والغثيان من أكثر الآثار الجانبية المرتبطة بعلاجات السرطان والتي تسبب الخوف لمرضى السرطان وعائلاتهم. ففي عام 1983 وجد كوتس وآخرون أن المرضى الذين يتلقون علاجا كيميائيا صنفوا القيء والغثيان كأولى الآثار الجانبية الأكثر شدة على التوالي. ووجد أن 20% من الذين يعانون من غثيان وقيء شديدين في العلاج يأجلون أو حتى يرفضون العلاجات الدوائية المحتمل تسببها لذلك. في التسعينات طُورت العديد من الفئات الجديدة المقاومة للغثيان تجاريا لتصبح مقياسا عالميا جديدا في نظم العلاجات الكيميائية، كما تساعد في إدارة تلك الأعراض لعدد كبير من المرضى. يؤدي هذا التدخل الفعال غير المرغوب والأعراض المدمرة أحيانا إلى زيادة جودة حياة المرضى وبالتالي فإن زيادة تحمل المرضى يؤدي لدورات علاجية أكثر فاعلية. (ar)
  • Chemotherapy-induced nausea and vomiting (CINV) is a common side-effect of many cancer treatments. Nausea and vomiting are two of the most feared cancer treatment-related side effects for cancer patients and their families. In 1983, Coates et al. found that patients receiving chemotherapy ranked nausea and vomiting as the first and second most severe side effects, respectively. Up to 20% of patients receiving highly emetogenic agents in this era postponed, or even refused, potentially curative treatments. Since the 1990s, several novel classes of antiemetics have been developed and commercialized, becoming a nearly universal standard in chemotherapy regimens, and helping to better manage these symptoms in a large portion of patients. Efficient mediation of these unpleasant and sometimes cr (en)
  • A náusea e vômito induzidos por quimioterapia (abreviado NVIQ, na literatura em inglês CINV, chemotherapy-induced nausea and vomiting) são um efeito colateral comum de muitos tratamentos contra o câncer. Náuseas e vômitos são dois dos efeitos colaterais relacionados ao tratamento de câncer mais temidos para pacientes com câncer e suas famílias. Em 1983, Coates et al. descobriram que os pacientes que receberam quimioterapia classificaram náuseas e vômitos como o primeiro e segundo efeitos colaterais mais graves, respectivamente. Até 20% dos pacientes que receberam agentes altamente emetogênicos nesta época adiaram, ou até mesmo recusaram, tratamentos potencialmente curativos. Desde a década de 1990, várias novas classes de antieméticos foram desenvolvidas e comercializadas, tornando-se um p (pt)
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  • الغثيان والقيء الناجم عن العلاج الكيميائي (ar)
  • Chemotherapy-induced nausea and vomiting (en)
  • Náusea e vômito induzidos por quimioterapia (pt)
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