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The three-base periodicity property in the field of Genomics is a property that is characteristic of protein-coding DNA sequences. The existence of this property can be shown by performing Fourier analysis on signals derived from segments of DNA sequences. Because of its predictive power, it has been used as a preliminary indicator in gene prediction.

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  • The three-base periodicity property in the field of Genomics is a property that is characteristic of protein-coding DNA sequences. The existence of this property can be shown by performing Fourier analysis on signals derived from segments of DNA sequences. Because of its predictive power, it has been used as a preliminary indicator in gene prediction. DNA sequences are inherently signals as they are functions of an independent variable, position on the sequence. Thus, signal processing methods can be applied to them after the symbolic string is properly mapped to one (or more) numerical sequences. The reason for this periodicity is due to the biased distribution towards codon triplets, which is a consequence of genetic code degeneracy; while non-coding segments are uniformly randomly distributed and produce no significant signal in the frequency space. (en)
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  • The three-base periodicity property in the field of Genomics is a property that is characteristic of protein-coding DNA sequences. The existence of this property can be shown by performing Fourier analysis on signals derived from segments of DNA sequences. Because of its predictive power, it has been used as a preliminary indicator in gene prediction. (en)
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  • 3-Base Periodicity Property (en)
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