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- Theatrical release poster (en)
- Kevin Costner plays Alex Marshall , whose fellow University of Michigan alumni and close friends attend his funeral after his suicide. (en)
- Kevin Kline plays Harold Cooper, married to Sarah and owner of a small running shoe company being purchased by a large corporation, who hosts the friends after the funeral. Harold tries to help Nick find a new line of work, as he tried to help Alex. (en)
- Jeff Goldblum plays Michael Gold, a journalist for People magazine, who needs investors for a New York nightclub. During the college years Michael had a brief encounter with Meg that led to an abortion. (en)
- Glenn Close plays Sarah Cooper, who had a brief affair with Alex five years earlier, primarily out of compassion; Sarah now helps friend Meg’s goal to single motherhood by facilitating her impregnation by Harold. (en)
- Meg Tilly plays Chloe, Alex's girlfriend of four months who is much younger than Alex and had been living with him in Sarah and Harold’s basement. (en)
- William Hurt plays Nick Carlton, former talk-radio psychologist, now an impotent Vietnam vet and drug dealer. Nick and Karen dated steadily during their college years, but Karen remains aloof, busy flirting with Sam. (en)
- Tom Berenger plays Sam Weber, a television actor, who is approached by Meg to father her child, but refuses, feeling fatherhood is too great a responsibility as he already has an estranged child. (en)
- JoBeth Williams plays Karen Bowens, an unfulfilled writer unhappily married to Richard, a conservative advertising executive, who harbors long-smoldering feelings for Sam that he encourages noncommittally. (en)
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