About: Hit to lead

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Stage of drug discovery

Property	Value
dbo:description	stage of drug discovery (en)
dbo:wikiPageWikiLink	dbr:Drug_metabolism dbr:Structure–activity_relationship dbr:Binding_selectivity dbr:Cytotoxicity dbr:Molar_concentration dbr:Conformational_change dbr:Isothermal_titration_calorimetry dbc:Pharmaceutical_industry dbr:Organic_chemistry dbr:Thermodynamics dbc:Drug_discovery dbr:High-throughput_screening dbr:P-glycoprotein dbr:Structural_analog dbr:Biological_target dbr:Combinatorial_chemistry dbr:Lead_compound dbr:Lipophilicity dbr:Partition_coefficient dbr:Surface_plasmon_resonance dbr:Dynamic_light_scattering dbr:Drug_discovery dbr:Nuclear_magnetic_resonance dbr:Stoichiometry dbr:Pharmaceutical_company dbr:Ligand_efficiency dbr:Serum_albumin dbr:Dual_polarisation_interferometry dbr:Cheminformatics dbr:Intrinsic_activity dbr:Small_molecule dbr:Lead_optimization dbr:P450 dbr:EC50 dbr:IC50 dbr:Pharmacokinetics dbr:Drug_design dbr:Preclinical_development dbr:Drug_development dbr:Receptor–ligand_kinetics dbr:ADME-Tox dbr:High-content_screening dbr:Druglikeness dbr:Microscale_thermophoresis dbr:Animal_model dbr:Quantitative_structure-activity_relationship dbr:Binding_affinity dbr:Fragment-based_lead_discovery dbr:Freedom_to_operate dbr:Lipophilic_efficiency dbr:Metabolic_half_life dbr:Rational_drug_design
dbp:wikiPageUsesTemplate	dbt:Columns-list dbt:Reflist dbt:Drug_design dbt:Short_description
dct:subject	dbc:Drug_discovery
gold:hypernym	dbr:Stage
rdfs:label	Hit to lead (en) リードジェネレーション (創薬) (ja)
owl:sameAs	freebase:Hit to lead wikidata:Hit to lead dbpedia-ja:Hit to lead dbpedia-he:Hit to lead dbpedia-global:Hit to lead
prov:wasDerivedFrom	wikipedia-en:Hit_to_lead?oldid=1292076410&ns=0
foaf:isPrimaryTopicOf	wikipedia-en:Hit_to_lead
is dbo:wikiPageRedirects of	dbr:Lead_optimization dbr:Lead_optimization dbr:Drug_Discovery_Hit_to_Lead dbr:Drug_discovery_hit_to_lead dbr:H2L
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is rdfs:seeAlso of	dbr:Medicinal_chemistry
is foaf:primaryTopic of	wikipedia-en:Hit_to_lead