Madeline Kneberg Lewis (1903–1996) was an American archaeologist and professor of anthropology at the University of Tennessee. She is most famous for her work on excavations in the Tennessee Valley, beginning in the 1930s. She was instrumental in establishing the anthropology department at the University of Tennessee as well as the Frank H. McClung Museum. She was the first female full professor at Tennessee outside of home economics and among the first prominent female archaeologists in the United States.