Ellen O'Keefe was an Irish immigrant to New York City, who took up nursing. Her experience led her to open a women's shelter, and later to found a religious congregation to continue her work. St. Zita's Home for Friendless Women was established at 158 East 24th Street, New York City, in 1890. It soon moved to West 14th Street, where it remained until it ceased operations around 2002.
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