The 2021–22 UCLA Bruins women's basketball team represented the University of California, Los Angeles during the 2021–22 NCAA Division I women's basketball season. The Bruins were led by eleventh-year head coach Cori Close. They played their home games at Pauley Pavilion and competed as members of the Pac-12 Conference. The Bruins were invited to the WNIT as the automatic qualifier for the Pac-12 Conference. It was the Bruins' first WNIT appearance since 2015, when they were WNIT champions.