The 2018–19 Syracuse Orange women's basketball team represents Syracuse University during the 2018–19 NCAA Division I women's basketball season. The Orange, led by twelfth year head coach Quentin Hillsman. The Orange were sixth year members of the Atlantic Coast Conference and play their home games at the Carrier Dome. They finished the season 25–9, 11–5 in ACC play to finish in fifth place. They advanced to the semifinals of the ACC women's tournament where they lost to Notre Dame. They received an at-large bid to the NCAA women's tournament, receiving a No. 3 seed in the Portland regional, where they defeated Fordham in the first round before being upset by South Dakota State in the second round.