The 2018–19 Duquesne Dukes women's basketball team will represent Duquesne University during the 2018–19 NCAA Division I women's basketball season. The Dukes were led by sixth year head coach Dan Burt. The Dukes were members of the Atlantic 10 Conference and play their home games at the Palumbo Center. They finished the season 19–13, 11–5 in A-10 play to finish in third place. They advance to the semifinals of the A-10 women's tournament where they lost to Fordham. Despite having 19 wins, they were not invited to a postseason tournament for the first time since 2008.