The 2018–19 SIU Edwardsville Cougars men's basketball team represented Southern Illinois University Edwardsville during the 2018–19 NCAA Division I men's basketball season. The Cougars, led by fourth-year head coach Jon Harris, played their home games at the Vadalabene Center in Edwardsville, Illinois as members of the Ohio Valley Conference. They finished the season 10–21, 6–12 in OVC play to finish in a four-way tie for seventh place. As the No. 8 seed, they lost in the first round of the OVC tournament to Morehead State.