The 2018–19 Eastern Illinois Panthers men's basketball team represented Eastern Illinois University during the 2018–19 NCAA Division I men's basketball season. The Panthers, led by seventh-year head coach Jay Spoonhour, played their home games at Lantz Arena as members of the Ohio Valley Conference. They finished the season 14–18, 7–11 in OVC play to finish in sixth place. They lost to UT Martin in the first round of the OVC tournament.