The 2015–16 Saint Louis Billikens men's basketball team represented Saint Louis University in the 2015–16 NCAA Division I men's basketball season. The Billikens were led by fourth year head coach Jim Crews. The team played their home games at Chaifetz Arena. They were a member of the Atlantic 10 Conference. They finished the season with an 11–22, 5–13 in A-10 play to finish in a tie for 12th place. They defeated George Mason in the first round of the A-10 tournament to advance to the second round where they lost to George Washington.