The 2015–16 Louisville Cardinals men's basketball team represented the University of Louisville during the 2015–16 NCAA Division I men's basketball season. This was Louisville's 102nd season of intercollegiate competition. The Cardinals competed in their second season in the Atlantic Coast Conference and were coached by Rick Pitino, in his 15th season at U of L. The team played its home games on Denny Crum Court at the KFC Yum! Center in downtown Louisville. They finished the season 23–8, 12–6 in ACC play to finish in fourth place.