Melbourne tram route 112 was operated by Yarra Trams on the Melbourne tram network from West Preston to St Kilda. The 18 kilometre route was operated out of East Preston depot with A, B and D2 class trams. The route number was introduced in 2002, and was discontinued on 27 July 2014 as part of a wider timetable change to the Yarra Trams network. This saw route 112 replaced by routes 11 and 12.