John Pollexfen (1636–1715), of Walbrooke House in the parish of St Stephen Walbrook, City of London and of Wembury House in Devon, was a merchant, a courtier to Kings Charles II and William III, and a political economist who served four times as a Member of Parliament for Plympton Erle in Devon, in 1679, 1681, 1689 and 1690. He was opposed to the monopoly of the East India Company.