The 2022 Premier Volleyball League Open Conference was the eleventh conference of the Premier Volleyball League (38th conference of the former Shakey's V-League) and its second conference as a professional league. Nine teams competed on this conference as Chery Tiggo 7 Pro Crossovers looks to defend their championship. F2 Logistics Cargo Movers will have their debut in the Premier Volleyball League. Two teams from the previous conference, Sta. Lucia Lady Realtors and Perlas Spikers, filed for leave of absence from the league and released all of their players.