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Зервас, Леонидас Leonidas Zervas Λεωνίδας Ζέρβας Leonidas Zervas
rdfs:comment
Leonidas Zervas (Greek: Λεωνίδας Ζέρβας, pronounced [leoˈniðas ˈzervas]; 21 May 1902 – 10 July 1980) was a Greek organic chemist who made seminal contributions in peptide chemical synthesis. Together with his mentor Max Bergmann they laid the foundations for the field in 1932 with their major discovery, the Bergmann-Zervas carboxybenzoxy oligopeptide synthesis which remained unsurpassed in utility for the next two decades. The carboxybenzyl protecting group he discovered is often abbreviated Z in his honour. Ο Λεωνίδας Ζέρβας (Μεγαλόπολη Αρκαδίας 21 Μαΐου 1902 − Αθήνα 10 Ιουλίου 1980) ήταν Έλληνας χημικός και μέλος της Ακαδημίας Αθηνών. Τιμήθηκε με πολλά βραβεία και παράσημα στην Ελλάδα και στο εξωτερικό. Leonidas Zervas (* 21. Mai 1902 in Megalopolis; † 10. Juli 1980 in Athen) war ein griechischer Chemiker (Organische Chemie). Леонидас Зервас (греч.: Λεωνίδας Ζέρβας, 21 мая 1902, Мегалополис — 10 июля 1980, Афины) — греческий химик-органик, внесший значительный вклад в химический синтез пептидов. Вместе со своим наставником они заложили основы этой области в 1932 году, сделав свое главное открытие - синтез , которые оставались непревзойденными по полезности в течение следующих двух десятилетий. Бензилоксикарбонильная защитная группа, которую он открыл, часто обозначается сокращенно Z (в русскоязычной литературе чаще встречается вариант Cbz-) в его честь.
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Leonidas Zervas
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Leonidas Zervas
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Athens, Greece
dbo:deathDate
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1902-05-21
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dbp:thesisTitle
Über die Aldehydverbindungen der Aminosäuren
dbp:thesisYear
1926
dbp:workplaces
*Kaiser Wilhelm Institute for Leather Research *Rockefeller Institute for Medical Research *Aristotle University of Thessaloniki *University of Athens *National Cancer Institute *Greek Atomic Energy Commission *Academy of Athens *National Hellenic Research Foundation
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dbo:thumbnail
n15:Cbz.png?width=300
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center
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dbp:alt
dibenzyl chlorophosphonate N-tritylamino acid ortho-nitrophenylsulfenyl chloride
dbp:awards
*Member of the Academy of Athens *Honorary Membership of the American Society of Biological Chemists *Order of Scientific Merit of the SR of Romania *Foreign Member of the USSR Academy of Sciences *Max Bergmann Golden Medal
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1902-05-21
dbp:caption
NPS-Cl used by Zervas to add the NPS group Optically pure N-tritylamino acid prepared by Zervas Dibenzyl chlorophosphonate, promoted by Zervas for amino acid N- or O- phosphorylation
dbp:deathDate
1980-07-10
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O-nitrophenylsulfenyl chloride.svg N-tritylamino acid.svg Dibenzyl chlorophosphonate.svg
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Carboxybenzyl protecting group, Peptide synthesis
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Λεωνίδας Ζέρβας
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el
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Hildegard Lange
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180 158 112
dbo:abstract
Леонидас Зервас (греч.: Λεωνίδας Ζέρβας, 21 мая 1902, Мегалополис — 10 июля 1980, Афины) — греческий химик-органик, внесший значительный вклад в химический синтез пептидов. Вместе со своим наставником они заложили основы этой области в 1932 году, сделав свое главное открытие - синтез , которые оставались непревзойденными по полезности в течение следующих двух десятилетий. Бензилоксикарбонильная защитная группа, которую он открыл, часто обозначается сокращенно Z (в русскоязычной литературе чаще встречается вариант Cbz-) в его честь. На протяжении своей жизни Зервас также занимал многие важные посты, в том числе пост президента Афинской академии, а также некоторое время пост министра промышленности Греции . Он получил множество наград при жизни и посмертно, таких как звание иностранного члена Академии наук СССР или первую золотую медаль Макса Бергмана. Leonidas Zervas (* 21. Mai 1902 in Megalopolis; † 10. Juli 1980 in Athen) war ein griechischer Chemiker (Organische Chemie). Ο Λεωνίδας Ζέρβας (Μεγαλόπολη Αρκαδίας 21 Μαΐου 1902 − Αθήνα 10 Ιουλίου 1980) ήταν Έλληνας χημικός και μέλος της Ακαδημίας Αθηνών. Τιμήθηκε με πολλά βραβεία και παράσημα στην Ελλάδα και στο εξωτερικό. Leonidas Zervas (Greek: Λεωνίδας Ζέρβας, pronounced [leoˈniðas ˈzervas]; 21 May 1902 – 10 July 1980) was a Greek organic chemist who made seminal contributions in peptide chemical synthesis. Together with his mentor Max Bergmann they laid the foundations for the field in 1932 with their major discovery, the Bergmann-Zervas carboxybenzoxy oligopeptide synthesis which remained unsurpassed in utility for the next two decades. The carboxybenzyl protecting group he discovered is often abbreviated Z in his honour. Throughout his life Zervas also served in many important posts, including President of the Academy of Athens or briefly Minister of Industry of Greece. He received numerous awards and honours during his life and posthumously, such as Foreign Member of the USSR Academy of Sciences or the first Max Bergmann golden medal.
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25
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