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Take Charge Brandi (foaled 7 February 2012) is an American Thoroughbred racehorse. A descendant of the outstanding broodmare Take Charge Lady, she was one of the leading juvenile fillies in North America in 2014. After winning only one of her first five races she sprang a 66/1 upset when winning the Breeders' Cup Juvenile Fillies and followed up with victories in the Delta Princess Stakes and the Grade I Starlet Stakes. After winning a listed stakes race early in 2015, a bone chip in her knee, discovered prior to her anticipated start in the Rebel Stakes, took her out of contention for the Kentucky Oaks. Returning to the track in August 2015, following two lackluster performances, she was retired in September, 2015.