About: Mazapertine

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org:8891

Mazapertine (RWJ-37796) is an antipsychotic agent that was developed by Johnson & Johnson but never marketed. It exerts its pharmacological effect through affinity for dopamine D2, serotonin 5-HT1A, and α1-adrenergic receptors. Mazapertine is safe and well tolerated when administered orally. Analogs of mazapertine with conformational restriction have been prepared and have greater affinity for the 5-HT1A receptor.

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dbo:abstract
  • Mazapertine (RWJ-37796) is an antipsychotic agent that was developed by Johnson & Johnson but never marketed. It exerts its pharmacological effect through affinity for dopamine D2, serotonin 5-HT1A, and α1-adrenergic receptors. Mazapertine is safe and well tolerated when administered orally. Analogs of mazapertine with conformational restriction have been prepared and have greater affinity for the 5-HT1A receptor. (en)
  • マザペルチン(Mazapertine、RWJ-37796)は、抗精神病薬である。 (ja)
dbo:alternativeName
  • RWJ-37796 (en)
dbo:iupacName
  • (Piperidin-1-yl){3-[(4-{2-[(propan-2-yl)oxy]phenyl}piperazin-1-yl)methyl]phenyl}methanone (en)
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  • 33934497 (xsd:integer)
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  • 5388 (xsd:nonNegativeInteger)
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  • 1122581286 (xsd:integer)
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  • Mazapertine.svg (en)
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  • 200 (xsd:integer)
dbp:othernames
  • RWJ-37796 (en)
dbp:pin
  • {3-[methyl]phenyl}methanone (en)
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  • Mazapertine (RWJ-37796) is an antipsychotic agent that was developed by Johnson & Johnson but never marketed. It exerts its pharmacological effect through affinity for dopamine D2, serotonin 5-HT1A, and α1-adrenergic receptors. Mazapertine is safe and well tolerated when administered orally. Analogs of mazapertine with conformational restriction have been prepared and have greater affinity for the 5-HT1A receptor. (en)
  • マザペルチン(Mazapertine、RWJ-37796)は、抗精神病薬である。 (ja)
rdfs:label
  • マザペルチン (ja)
  • Mazapertine (en)
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