About: Mazapertine

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Mazapertine (RWJ-37796) is an antipsychotic agent that was developed by Johnson & Johnson but never marketed. It exerts its pharmacological effect through affinity for dopamine D2, serotonin 5-HT1A, and α1-adrenergic receptors. Mazapertine is safe and well tolerated when administered orally. Analogs of mazapertine with conformational restriction have been prepared and have greater affinity for the 5-HT1A receptor.

Property Value
dbo:abstract
  • Mazapertine (RWJ-37796) is an antipsychotic agent that was developed by Johnson & Johnson but never marketed. It exerts its pharmacological effect through affinity for dopamine D2, serotonin 5-HT1A, and α1-adrenergic receptors. Mazapertine is safe and well tolerated when administered orally. Analogs of mazapertine with conformational restriction have been prepared and have greater affinity for the 5-HT1A receptor. (en)
  • マザペルチン(Mazapertine、RWJ-37796)は、抗精神病薬である。 (ja)
dbo:alternativeName
  • RWJ-37796 (en)
dbo:iupacName
  • (Piperidin-1-yl){3-[(4-{2-[(propan-2-yl)oxy]phenyl}piperazin-1-yl)methyl]phenyl}methanone (en)
dbo:thumbnail
dbo:wikiPageID
  • 33934497 (xsd:integer)
dbo:wikiPageLength
  • 5388 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1122581286 (xsd:integer)
dbo:wikiPageWikiLink
dbp:imagefile
  • Mazapertine.svg (en)
dbp:imagesize
  • 200 (xsd:integer)
dbp:othernames
  • RWJ-37796 (en)
dbp:pin
  • {3-[methyl]phenyl}methanone (en)
dbp:wikiPageUsesTemplate
dcterms:subject
gold:hypernym
rdf:type
rdfs:comment
  • Mazapertine (RWJ-37796) is an antipsychotic agent that was developed by Johnson & Johnson but never marketed. It exerts its pharmacological effect through affinity for dopamine D2, serotonin 5-HT1A, and α1-adrenergic receptors. Mazapertine is safe and well tolerated when administered orally. Analogs of mazapertine with conformational restriction have been prepared and have greater affinity for the 5-HT1A receptor. (en)
  • マザペルチン(Mazapertine、RWJ-37796)は、抗精神病薬である。 (ja)
rdfs:label
  • マザペルチン (ja)
  • Mazapertine (en)
owl:sameAs
prov:wasDerivedFrom
foaf:depiction
foaf:isPrimaryTopicOf
is dbo:wikiPageRedirects of
is dbo:wikiPageWikiLink of
is foaf:primaryTopic of
Powered by OpenLink Virtuoso    This material is Open Knowledge     W3C Semantic Web Technology     This material is Open Knowledge    Valid XHTML + RDFa
This content was extracted from Wikipedia and is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License