Along Delaware Route 141 there are a number of historic sites that trace the history of both the Du Pont family and the DuPont company. At the southwest end is DuPont’s Chestnut Run Plaza and at the northeastern end is the Alfred I. duPont Hospital for Children. Between are a number of sites on the National Register of Historic Places. The historic locations include equal portion of the history of the American chemical industry, the role of the DuPont family - their estates and gardens - and the philanthropy of a distinguished American family.