About: Datumetine

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org:8891

Datumetine is a tropane alkaloid found in leaves of Datura metel. It is said to modulate NMDA receptor and thus causes memory loss. It also causes epileptic seizures in mice. Docking studies suggest that it fits on both allosteric and sites of NMDA receptor. It acts together with other anticholinergic tropane alkaloids of datura to cause amnesia.

Property	Value
dbo:abstract	Datumetine is a tropane alkaloid found in leaves of Datura metel. It is said to modulate NMDA receptor and thus causes memory loss. It also causes epileptic seizures in mice. Docking studies suggest that it fits on both allosteric and sites of NMDA receptor. It acts together with other anticholinergic tropane alkaloids of datura to cause amnesia. (en)
dbo:iupacName	4-Methoxy-3-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)benzoic acid (en)
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dbo:wikiPageWikiLink	dbc:Tropane_alkaloids dbc:Tropane_alkaloids_found_in_Solanaceae dbc:Methoxy_compounds dbc:Phenyl_compounds dbr:Anticholinergic dbc:NMDA_receptor_modulators dbr:Datura_ferox dbr:Docking_(molecular) dbr:Allosteric dbr:Datura_metel dbc:Benzoic_acids dbr:NMDA_receptor dbr:Tropane_alkaloid dbr:Orthosteric
dbp:imagefile	Datumetine.svg (en)
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dcterms:subject	dbc:Tropane_alkaloids dbc:Tropane_alkaloids_found_in_Solanaceae dbc:Methoxy_compounds dbc:Phenyl_compounds dbc:NMDA_receptor_modulators dbc:Benzoic_acids
rdf:type	owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q11173 dbo:ChemicalCompound
rdfs:comment	Datumetine is a tropane alkaloid found in leaves of Datura metel. It is said to modulate NMDA receptor and thus causes memory loss. It also causes epileptic seizures in mice. Docking studies suggest that it fits on both allosteric and sites of NMDA receptor. It acts together with other anticholinergic tropane alkaloids of datura to cause amnesia. (en)
rdfs:label	Datumetine (en)
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prov:wasDerivedFrom	wikipedia-en:Datumetine?oldid=1124346029&ns=0
foaf:depiction	wiki-commons:Special:FilePath/Datumetine.svg
foaf:isPrimaryTopicOf	wikipedia-en:Datumetine
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