About: TM7x

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TM7x, also known as Nanosynbacter lyticus type strain TM7x HMT 952. is a phylotype of one of the most enigmatic phyla, Candidatus Saccharibacteria, formerly candidate phylum TM7. It is the only member of the candidate phylum that has been cultivated successfully from the human oral cavity, and stably maintained in vitro. and serves as a crucial paradigm. of the newly described Candidate Phyla Radiation (CPR). The cultivated oral taxon is designated as Saccharibacteria oral taxon TM7x (NCBI taxonomy ID: 1476577). TM7x has a unique lifestyle in comparison to other bacteria that are associated with humans. It is an obligate epibiont parasite, or an "epiparasite", growing on the surface of its host bacterial species Actinomyces odontolyticus subspecies actinosynbacter strain XH001, which is re

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  • TM7x, also known as Nanosynbacter lyticus type strain TM7x HMT 952. is a phylotype of one of the most enigmatic phyla, Candidatus Saccharibacteria, formerly candidate phylum TM7. It is the only member of the candidate phylum that has been cultivated successfully from the human oral cavity, and stably maintained in vitro. and serves as a crucial paradigm. of the newly described Candidate Phyla Radiation (CPR). The cultivated oral taxon is designated as Saccharibacteria oral taxon TM7x (NCBI taxonomy ID: 1476577). TM7x has a unique lifestyle in comparison to other bacteria that are associated with humans. It is an obligate epibiont parasite, or an "epiparasite", growing on the surface of its host bacterial species Actinomyces odontolyticus subspecies actinosynbacter strain XH001, which is referred to as the "basibiont". Actinomyces species are one of the early microbial colonizers in the oral cavity. Together, they exhibit parasitic epibiont symbiosis. The TM7 phylum was named with reference to the Torf, mittlere Schicht (or peat, middle layer) in which it was first detected in a German peat bog. The TM7 phylum correlates positively with various human inflammatory mucosal diseases. such as periodontitis. and particularly those conditions associated with a mature anaerobic biofilm. This is probably by modifying growth conditions for competing bacterial populations. The Saccharibacteria phylum has a cosmopolitan existence, devoid of any cultivable representative for more than 2 decades since the first RNA sequence was recovered. (except the recently cultivated oral taxon TM7x) and has thus been referred to as "microbial dark matter". Saccharibacteria are part of CPR which is a recently described expansion of the tree of life encompassing more than 15% of the bacterial domain, due to shared genomic characteristics with other novel genomes in the domain Bacteria. They display reduced metabolic capabilities and a parasitic lifestyle. along with their ability to promote biofilm formation capability of the host. (en)
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  • Nanosynbacter lyticus (en)
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  • Nanosynbacter (en)
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  • N. lyticus (en)
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  • TM7x, also known as Nanosynbacter lyticus type strain TM7x HMT 952. is a phylotype of one of the most enigmatic phyla, Candidatus Saccharibacteria, formerly candidate phylum TM7. It is the only member of the candidate phylum that has been cultivated successfully from the human oral cavity, and stably maintained in vitro. and serves as a crucial paradigm. of the newly described Candidate Phyla Radiation (CPR). The cultivated oral taxon is designated as Saccharibacteria oral taxon TM7x (NCBI taxonomy ID: 1476577). TM7x has a unique lifestyle in comparison to other bacteria that are associated with humans. It is an obligate epibiont parasite, or an "epiparasite", growing on the surface of its host bacterial species Actinomyces odontolyticus subspecies actinosynbacter strain XH001, which is re (en)
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  • TM7x (en)
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