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The Shannon criteria constitute an empirical rule in neural engineering that is used for evaluation of possibility of damage from electrical stimulation to nervous tissue. The Shannon criteria relate two parameters for pulsed electrical stimulation: charge density per phase, D (μCoulombs/(phase•cm²)) and charge per phase, Q (μCoulombs/phase) with a dimensionless parameter k: which can be written alternatively:

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  • The Shannon criteria constitute an empirical rule in neural engineering that is used for evaluation of possibility of damage from electrical stimulation to nervous tissue. The Shannon criteria relate two parameters for pulsed electrical stimulation: charge density per phase, D (μCoulombs/(phase•cm²)) and charge per phase, Q (μCoulombs/phase) with a dimensionless parameter k: which can be written alternatively: According to these criteria, stimulation parameters that yield k ≥ 1.85 (the lowest value where damage was observed in the two studies referenced in the original Shannon publication) could cause damage to the adjacent nervous tissue. Currently, this empirical law is applied in neuromodulation for development of implants for cortical, cochlear, retinal, and deep brain stimulation. Shannon categorizes the relationship between stimulating electrode and target neural tissue as either Near Field, Mid Field, or Far Field, and discusses how equation parameters may be chosen in each case. In the case of spinal cord stimulation, for example, the Far Field category would apply. (en)
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  • The Shannon criteria constitute an empirical rule in neural engineering that is used for evaluation of possibility of damage from electrical stimulation to nervous tissue. The Shannon criteria relate two parameters for pulsed electrical stimulation: charge density per phase, D (μCoulombs/(phase•cm²)) and charge per phase, Q (μCoulombs/phase) with a dimensionless parameter k: which can be written alternatively: (en)
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  • Shannon Criteria (en)
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