About: Sermorelin

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Sermorelin acetate (INN; brand names Geref, Gerel), also known as GHRH (1-29), is a peptide analogue of growth hormone-releasing hormone (GHRH) which is used as a diagnostic agent to assess growth hormone (GH) secretion for the purpose of diagnosing growth hormone deficiency. It is a 29-amino acid polypeptide representing the 1–29 fragment from endogenous human GHRH, thought to be the shortest fully functional fragment of GHRH.

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dbo:abstract
  • Sermorelin acetate (INN; brand names Geref, Gerel), also known as GHRH (1-29), is a peptide analogue of growth hormone-releasing hormone (GHRH) which is used as a diagnostic agent to assess growth hormone (GH) secretion for the purpose of diagnosing growth hormone deficiency. It is a 29-amino acid polypeptide representing the 1–29 fragment from endogenous human GHRH, thought to be the shortest fully functional fragment of GHRH. (en)
  • La sermorelina è un analogo dell'ormone di rilascio della somatotropina umano (GHRH) di cui rappresenta il frammento 1-29. Viene utilizzata per la diagnosi e per il trattamento delle condizioni patologiche da deficit di ormone della crescita nei bambini in quanto stimola la produzione di tale ormone agonizzando i recettori del GHRH presenti nell'ipofisi. (it)
  • Sermorelina (INN: Sermorelin) – polipeptyd zbudowany z pierwszych 29 aminokwasów somatoliberyny, stosowany jest jako czynnik uwalniający somatotropinę w teście oceniającym zdolność komórek przedniego płata przysadki do wytwarzania hormonu wzrostu oraz w leczeniu niedoboru hormon wzrostu u dzieci. (pl)
dbo:alternativeName
  • Geref, Gerel (en)
dbo:casNumber
  • 86168-78-7
dbo:chEBI
  • 9118
dbo:chEMBL
  • 1201490
dbo:drugbank
  • DB00010
dbo:fdaUniiCode
  • 89243S03TE
dbo:kegg
  • D08509
dbo:pubchem
  • 16132413
dbo:wikiPageID
  • 11318480 (xsd:integer)
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  • 5695 (xsd:nonNegativeInteger)
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  • 993101701 (xsd:integer)
dbo:wikiPageWikiLink
dbp:atcPrefix
  • H01 (en)
dbp:atcSuffix
  • AC04 (en)
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  • 149 (xsd:integer)
dbp:casNumber
  • 86168 (xsd:integer)
dbp:chebi
  • 9118 (xsd:integer)
dbp:chembl
  • 1201490 (xsd:integer)
dbp:chemspiderid
  • 17289071 (xsd:integer)
dbp:drugbank
  • DB00010 (en)
dbp:h
  • 246 (xsd:integer)
dbp:iupacName
  • (L)-Tyrosyl-(L)-alanyl-(L)-α-aspartyl-(L)-alanyl-(L)-isoleucyl-(L)-phenylalanyl-(L)-threonyl-(L)-asparaginyl-(L)-seryl-(L)-tyrosyl-(L)-arginyl-(L)-lysyl-(L)-valyl-(L)-leucylglycyl-(L)-glutaminyl-(L)-leucyl-(L)-seryl-(L)-alanyl-(L)-arginyl-(L)-lysyl-(L)-leucyl-(L)-leucyl-(L)-glutaminyl-(L)-α-aspartyl-(L)-isoleucyl-(L)-methionyl-(L)-seryl-(L)-argininamide (en)
dbp:kegg
  • D08509 (en)
dbp:legalUs
  • Discontinued (en)
dbp:n
  • 44 (xsd:integer)
dbp:o
  • 42 (xsd:integer)
dbp:pregnancyUs
  • C (en)
dbp:pubchem
  • 16132413 (xsd:integer)
dbp:routesOfAdministration
  • Injection (en)
dbp:s
  • 1 (xsd:integer)
dbp:smiles
  • CC[C@H][C@@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]N (en)
dbp:stdinchi
  • 1 (xsd:integer)
dbp:stdinchikey
  • WGWPRVFKDLAUQJ-MITYVQBRSA-N (en)
dbp:synonyms
  • GRF 1–29 (en)
dbp:tradename
  • Geref, Gerel (en)
dbp:unii
  • 89243 (xsd:integer)
dbp:verifiedfields
  • changed (en)
dbp:verifiedrevid
  • 409589124 (xsd:integer)
dbp:watchedfields
  • changed (en)
dbp:wikiPageUsesTemplate
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gold:hypernym
rdf:type
rdfs:comment
  • Sermorelin acetate (INN; brand names Geref, Gerel), also known as GHRH (1-29), is a peptide analogue of growth hormone-releasing hormone (GHRH) which is used as a diagnostic agent to assess growth hormone (GH) secretion for the purpose of diagnosing growth hormone deficiency. It is a 29-amino acid polypeptide representing the 1–29 fragment from endogenous human GHRH, thought to be the shortest fully functional fragment of GHRH. (en)
  • La sermorelina è un analogo dell'ormone di rilascio della somatotropina umano (GHRH) di cui rappresenta il frammento 1-29. Viene utilizzata per la diagnosi e per il trattamento delle condizioni patologiche da deficit di ormone della crescita nei bambini in quanto stimola la produzione di tale ormone agonizzando i recettori del GHRH presenti nell'ipofisi. (it)
  • Sermorelina (INN: Sermorelin) – polipeptyd zbudowany z pierwszych 29 aminokwasów somatoliberyny, stosowany jest jako czynnik uwalniający somatotropinę w teście oceniającym zdolność komórek przedniego płata przysadki do wytwarzania hormonu wzrostu oraz w leczeniu niedoboru hormon wzrostu u dzieci. (pl)
rdfs:label
  • Sermorelina (it)
  • Sermorelina (pl)
  • Sermorelin (en)
owl:sameAs
prov:wasDerivedFrom
foaf:isPrimaryTopicOf
is dbo:wikiPageRedirects of
is dbo:wikiPageWikiLink of
is foaf:primaryTopic of
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