About: SERPIN A12

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Serpin A12 (OL-64, Vaspin, Visceral adipose-specific serpin, Ser A12) is a glycoprotein that is a class A member of the serine protease inhibitor (serpin) family. In humans, Serpin A12 is encoded by the SERPINA12 gene.

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  • La vaspina (sigla parcial del inglés visceral adipose serpin protease inhibitor), o serpina A12, también conocida como OL-64, es una proteína inhibidora de la enzima serina proteasa. Esta adipocina también es un sensibilizador de insulina, una cardioprotectora y antiarteriosclerótica. Se encuentra en el tejido adiposo visceral y en el sistema circulatorio. Esta molécula pertenece a la familia de las serpinas, concretamente a las de clase A. (es)
  • Serpin A12 (OL-64, Vaspin, Visceral adipose-specific serpin, Ser A12) is a glycoprotein that is a class A member of the serine protease inhibitor (serpin) family. In humans, Serpin A12 is encoded by the SERPINA12 gene. First discovered in 2005, Serpin A12 was highly expressed in white adipose tissue of Otsuka Long Evans Tokushima Fatty Rats at the same time that the rats' obesity and insulin plasma levels reached a peak, at around 30 weeks old. Eventually, it was found to be expressed in visceral and subcutaneous adipose tissue of obese humans, leading the protein to be linked with obesity, glucose metabolism, and insulin resistance. (en)
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  • La vaspina (sigla parcial del inglés visceral adipose serpin protease inhibitor), o serpina A12, también conocida como OL-64, es una proteína inhibidora de la enzima serina proteasa. Esta adipocina también es un sensibilizador de insulina, una cardioprotectora y antiarteriosclerótica. Se encuentra en el tejido adiposo visceral y en el sistema circulatorio. Esta molécula pertenece a la familia de las serpinas, concretamente a las de clase A. (es)
  • Serpin A12 (OL-64, Vaspin, Visceral adipose-specific serpin, Ser A12) is a glycoprotein that is a class A member of the serine protease inhibitor (serpin) family. In humans, Serpin A12 is encoded by the SERPINA12 gene. (en)
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  • Vaspina (es)
  • SERPIN A12 (en)
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