An Entity of Type: disease, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Progressive vaccinia is a rare cutaneous condition caused by the vaccinia virus, characterized by painless but progressive necrosis and ulceration.

Property Value
dbo:abstract
  • Η προοδευτική δαμαλίτιδα είναι μια σπάνια που προκαλείται από τον ιό της , ο οποίος χαρακτηρίζεται από μια ανώδυνη αλλά αυξανόμενη νέκρωση και έλκος. (el)
  • الوقس المترقي، حالة جلدية نادرة يسببها فيروس الوقس، ويتميز بتنخر وتقرح غير مؤلم ولكنه مترقي. (ar)
  • Progressive vaccinia is a rare cutaneous condition caused by the vaccinia virus, characterized by painless but progressive necrosis and ulceration. (en)
dbo:complications
  • Necrosisof the injected part, exacerbating togangreneand eventual amputation. Usually, the pocks tend to go away without scarring; however, the external and internal spread of the virus may have serious consequences in persons with eczema and other forms of atopic dermatitis, in these persons, defects of innate immunity and a high level of Th2 cell activity render the skin unusually permissive to the initiation and rapid spread of vaccinia infection (known as “eczema vaccinatum”)
dbo:differentialDiagnosis
dbo:medicalCause
dbo:medicalDiagnosis
dbo:medicalSpecialty
dbo:medication
dbo:symptom
dbo:synonym
  • Vaccinia gangrenosum, Vaccinia necrosum or disseminated vaccinia
dbo:thumbnail
dbo:treatment
dbo:wikiPageID
  • 22827385 (xsd:integer)
dbo:wikiPageLength
  • 11893 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1107993229 (xsd:integer)
dbo:wikiPageWikiLink
dbp:alt
  • Necrotic tissue on shoulder (en)
dbp:caption
  • The patient required a skin graft on her upper left arm in order to correct the necrotic vaccination site, due to the onset of progressive vaccinia, formerly known as vaccinia gangrenosum. (en)
dbp:causes
  • Injection by the vaccinia virus as a countermeasure for smallpox (en)
dbp:complications
  • Necrosis of the injected part, exacerbating to gangrene and eventual amputation. Usually, the pocks tend to go away without scarring; however, the external and internal spread of the virus may have serious consequences in persons with eczema and other forms of atopic dermatitis, in these persons, defects of innate immunity and a high level of Th2 cell activity render the skin unusually permissive to the initiation and rapid spread of vaccinia infection (en)
dbp:deaths
  • fatality rate: 15% (en)
dbp:diagnosis
  • Fever and headache, then progressive ulceration and necrosis of the injection site for smallpox, albeit the lack of inflammation is noted as the "hallmark of PV" (en)
dbp:differential
  • May initially be mistaken for leukemia (en)
dbp:duration
  • Long-lasting (en)
dbp:frequency
  • every 1 or 2 in a million during routine vaccination during 1963-1968 for smallpox (en)
dbp:imageSize
  • 250 (xsd:integer)
dbp:medication
  • Imiquimod, and thiosemicarbazone (en)
dbp:name
  • Progressive vaccinia (en)
dbp:onset
  • 950400.0
dbp:prevention
  • Unknown (en)
dbp:prognosis
  • Lifelong (en)
dbp:risks
  • People with cellular immunodeficiencies (en)
dbp:specialty
dbp:symptoms
  • Malaise, fever, vomiting and tender, enlarged axillary lymph nodes; progresses to septic Pseudomonas aeruginosa, likely from a perirectal abscess, Clostridium difficile (bacteria), Staphylococcus aureus and cell-mediated immunodeficiency. (en)
dbp:synonym
  • Vaccinia gangrenosum, Vaccinia necrosum or disseminated vaccinia (en)
dbp:treatment
  • Vaccinia Immune Globulin Intravenous , Emergency Investigational New Drug both administered orally and topically, ; CMX001, a lipid conjugate of cidofovir and granulocyte colony-stimulating factor for the exiguous normal white blood cells;supportive care; skin graft (en)
dbp:wikiPageUsesTemplate
dcterms:subject
gold:hypernym
rdf:type
rdfs:comment
  • Η προοδευτική δαμαλίτιδα είναι μια σπάνια που προκαλείται από τον ιό της , ο οποίος χαρακτηρίζεται από μια ανώδυνη αλλά αυξανόμενη νέκρωση και έλκος. (el)
  • الوقس المترقي، حالة جلدية نادرة يسببها فيروس الوقس، ويتميز بتنخر وتقرح غير مؤلم ولكنه مترقي. (ar)
  • Progressive vaccinia is a rare cutaneous condition caused by the vaccinia virus, characterized by painless but progressive necrosis and ulceration. (en)
rdfs:label
  • وقس مترقي (ar)
  • Προοδευτική δαμαλίτιδα (el)
  • Progressive vaccinia (en)
owl:sameAs
prov:wasDerivedFrom
foaf:depiction
foaf:isPrimaryTopicOf
foaf:name
  • Progressive vaccinia (en)
is dbo:wikiPageRedirects of
is dbo:wikiPageWikiLink of
is dbp:types of
is foaf:primaryTopic of
Powered by OpenLink Virtuoso    This material is Open Knowledge     W3C Semantic Web Technology     This material is Open Knowledge    Valid XHTML + RDFa
This content was extracted from Wikipedia and is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License