About: Pairwise Algorithm
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A Pairwise Algorithm is an algorithmic technique with its origins in Dynamic programming. Pairwise algorithms have several uses including comparing a protein profile (a residue scoring matrix for one or more aligned sequences) against the three translation frames of a DNA strand, allowing frameshifting. The most remarkable feature of PairWise as compared to other Protein-DNA alignment tools is that PairWise allows frameshifting during alignment.
