About: PF-592,379

Property	Value
dbo:abstract	بي أف-592,379 (بالإنجليزية: PF-592,379)‏ هو دواء طورته فايزر وهو قوي وانتقائي . الدواء تحت الدراسة بسبب احتمال فعاليته في علاج وضعف الانتصاب عند الرجال. بخلاف ناهضات مستقبل الدوبامين د3 الانتقائية الأخرى، لم تظخر هذه المادة سوء استخدام محتمل. (ar) PF-592,379 is a drug developed by Pfizer which acts as a potent, selective and orally active agonist for the dopamine D3 receptor, which is under development as a potential medication for the treatment of female sexual dysfunction and male erectile dysfunction. Unlike some other less selective D3 agonists, a research study showed that PF-592,379 has little abuse potential in animal studies, and so was selected for further development and potentially human clinical trials. Development has since been discontinued. (en)
dbo:casNumber	710655-15-5
dbo:fdaUniiCode	66B7UY5K7I
dbo:pubchem	10263487
dbo:thumbnail	wiki-commons:Special:FilePath/PF-592379_structure.png?width=300
dbo:wikiPageID	36515249 (xsd:integer)
dbo:wikiPageLength	3385 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID	1121456230 (xsd:integer)
dbo:wikiPageWikiLink	dbr:Pfizer dbc:Abandoned_drugs dbc:Pfizer_brands dbr:Erectile_dysfunction dbr:Functional_selectivity dbc:Aphrodisiacs dbr:7-OH-DPAT dbr:Agonist dbr:Drug_development dbc:Female_sexual_dysfunction_drugs dbr:PD-128,907 dbr:PF-219,061 dbr:Female_sexual_dysfunction dbr:Receptor_(biochemistry) dbc:Aminopyridines dbc:Dopamine_agonists dbc:Morpholines dbr:Dopamine dbr:D3_receptor
dbp:c	13 (xsd:integer)
dbp:casNumber	710655 (xsd:integer)
dbp:chemspiderid	8438966 (xsd:integer)
dbp:h	21 (xsd:integer)
dbp:iupacName	5 (xsd:integer)
dbp:iupharLigand	7683 (xsd:integer)
dbp:legalStatus	Investigational (en)
dbp:n	3 (xsd:integer)
dbp:o	1 (xsd:integer)
dbp:pubchem	10263487 (xsd:integer)
dbp:routesOfAdministration	Oral (en)
dbp:smiles	CCCNC[C@H]1C2=CN=CC=C2 (en)
dbp:stdinchi	1 (xsd:integer)
dbp:stdinchikey	DFTCYTDJDXZFSK-JQWIXIFHSA-N (en)
dbp:unii	66 (xsd:integer)
dbp:width	260 (xsd:integer)
dbp:wikiPageUsesTemplate	dbt:Dopaminergics dbt:Drugbox dbt:Reflist dbt:Short_description dbt:Cascite dbt:Drugbankcite dbt:Fdacite
dcterms:subject	dbc:Abandoned_drugs dbc:Pfizer_brands dbc:Aphrodisiacs dbc:Female_sexual_dysfunction_drugs dbc:Aminopyridines dbc:Dopamine_agonists dbc:Morpholines
gold:hypernym	dbr:Drug
rdf:type	owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:Agent114778436 yago:CausalAgent100007347 yago:Drug103247620 yago:Matter100020827 yago:PhysicalEntity100001930 dbo:Drug yago:Substance100020090 yago:WikicatFemaleSexualDysfunctionDrugs
rdfs:comment	بي أف-592,379 (بالإنجليزية: PF-592,379)‏ هو دواء طورته فايزر وهو قوي وانتقائي . الدواء تحت الدراسة بسبب احتمال فعاليته في علاج وضعف الانتصاب عند الرجال. بخلاف ناهضات مستقبل الدوبامين د3 الانتقائية الأخرى، لم تظخر هذه المادة سوء استخدام محتمل. (ar) PF-592,379 is a drug developed by Pfizer which acts as a potent, selective and orally active agonist for the dopamine D3 receptor, which is under development as a potential medication for the treatment of female sexual dysfunction and male erectile dysfunction. Unlike some other less selective D3 agonists, a research study showed that PF-592,379 has little abuse potential in animal studies, and so was selected for further development and potentially human clinical trials. Development has since been discontinued. (en)
rdfs:label	بي أف-592379 (ar) PF-592,379 (en)
owl:sameAs	freebase:PF-592,379 yago-res:PF-592,379 wikidata:PF-592,379 dbpedia-ar:PF-592,379 dbpedia-sh:PF-592,379 dbpedia-sr:PF-592,379 https://global.dbpedia.org/id/4sogB
prov:wasDerivedFrom	wikipedia-en:PF-592,379?oldid=1121456230&ns=0
foaf:depiction	wiki-commons:Special:FilePath/PF-592379_structure.png
foaf:isPrimaryTopicOf	wikipedia-en:PF-592,379
is dbo:wikiPageWikiLink of	dbr:Dopamine_receptor_D3 dbr:PD-128,907 dbr:PF-219,061 dbr:C13H21N3O dbr:Substituted_phenylmorpholine
is foaf:primaryTopic of	wikipedia-en:PF-592,379