About: PD 144418

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

PD 144418 or 1,2,3,6-tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine is a potent and selective ligand for the sigma-1 receptor, with a reported binding affinity of Ki = 0.08 ± 0.01 nM, and 17 212 times selectivity over the sigma-2 receptor.

thumbnail
Property Value
dbo:abstract
  • PD 144418 or 1,2,3,6-tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine is a potent and selective ligand for the sigma-1 receptor, with a reported binding affinity of Ki = 0.08 ± 0.01 nM, and 17 212 times selectivity over the sigma-2 receptor. (en)
dbo:casNumber
  • 154130-99-1
dbo:thumbnail
dbo:wikiPageID
  • 36142813 (xsd:integer)
dbo:wikiPageLength
  • 2073 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1120576851 (xsd:integer)
dbo:wikiPageWikiLink
dbp:c
  • 18 (xsd:integer)
dbp:casNumber
  • 154130 (xsd:integer)
dbp:chemspiderid
  • 7992981 (xsd:integer)
dbp:h
  • 22 (xsd:integer)
dbp:iupacName
  • 1236 (xsd:integer)
dbp:n
  • 2 (xsd:integer)
dbp:o
  • 1 (xsd:integer)
dbp:smiles
  • CCCN1CCC=CC2=CCC3=CC=CC (en)
dbp:stdinchi
  • 1 (xsd:integer)
dbp:stdinchikey
  • FOQRKFCLRMMKAT-UHFFFAOYSA-N (en)
dbp:wikiPageUsesTemplate
dcterms:subject
gold:hypernym
rdf:type
rdfs:comment
  • PD 144418 or 1,2,3,6-tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine is a potent and selective ligand for the sigma-1 receptor, with a reported binding affinity of Ki = 0.08 ± 0.01 nM, and 17 212 times selectivity over the sigma-2 receptor. (en)
rdfs:label
  • PD 144418 (en)
owl:sameAs
prov:wasDerivedFrom
foaf:depiction
foaf:isPrimaryTopicOf
is dbo:wikiPageWikiLink of
is foaf:primaryTopic of
Powered by OpenLink Virtuoso    This material is Open Knowledge     W3C Semantic Web Technology     This material is Open Knowledge    Valid XHTML + RDFa
This content was extracted from Wikipedia and is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License